{"id":"W4290615255","doi":"10.1186/s13075-022-02877-9","title":"A randomized, double-blind, placebo-controlled 12-week trial of infliximab in patients with juvenile-onset spondyloarthritis","year":2022,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Health; University of Alberta","funders":"","keywords":"Medicine; Infliximab; Placebo; Internal medicine; Ankylosing spondylitis; Adverse effect; Clinical endpoint; Rheumatology; Sulfasalazine; Randomized controlled trial; Surgery; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003729705,0.0004266091,0.002424068,0.001026759,0.0006025744,0.00006314885,0.0003152145,0.0001164397,0.001682584],"category_scores_gemma":[0.00030961,0.0003458373,0.0004942739,0.001124475,0.0007718201,0.0001985181,0.0002484714,0.0009996304,0.00003087371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002828318,"about_ca_system_score_gemma":0.0005200715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008884703,"about_ca_topic_score_gemma":0.0007543279,"domain_scores_codex":[0.9926103,0.001692787,0.001224865,0.000754674,0.00260241,0.001114965],"domain_scores_gemma":[0.9970512,0.001111209,0.0002904186,0.0007540475,0.0005214742,0.000271675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9461076,0.00641129,0.01027711,0.00001594682,0.0007472789,0.0004912263,0.001204546,0.00001378644,0.00001640671,0.0001921264,0.0004722818,0.03405041],"study_design_scores_gemma":[0.9700382,0.02082008,0.001496066,0.0002276213,0.00003837711,0.0000535466,0.0005726864,0.00001608426,0.00008969333,0.00026578,0.006096511,0.0002852898],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715145,0.008100253,0.000002059625,0.0007617747,0.0002512587,0.01641316,0.0001776535,0.00005319003,0.002726161],"genre_scores_gemma":[0.9813107,0.006834276,0.0001360542,0.0001512238,0.0001125294,0.01041982,0.0002663572,0.00008857567,0.0006804441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03376512,"threshold_uncertainty_score":0.9998994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05057344740237421,"score_gpt":0.3328261670797753,"score_spread":0.2822527196774011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}