{"id":"W4290653701","doi":"10.1530/joe-22-0049","title":"Isoflurane stress induces region-specific glucocorticoid levels in neonatal mouse brain","year":2022,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Corticosterone; Glucocorticoid; Endocrinology; Internal medicine; Hippocampus; Stressor; Medicine; Isoflurane; Hormone; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001780586,0.0004585756,0.0003099352,0.0007596717,0.0002141745,0.0003758071,0.0003302727,0.0003168819,0.001260576],"category_scores_gemma":[0.000115729,0.000321527,0.0004228526,0.0002841726,0.0004872397,0.0003112808,0.0002943043,0.001257066,0.0004378755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005814008,"about_ca_system_score_gemma":0.0003876098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001819165,"about_ca_topic_score_gemma":0.005599085,"domain_scores_codex":[0.9996985,0.0000151964,0.00002255216,0.0001164229,0.00008944691,0.00005791463],"domain_scores_gemma":[0.9998055,0.00001468907,0.00007520329,0.00001962066,0.00002804915,0.00005701273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001326098,0.00001974633,0.0004047096,0.00002126068,0.000006965143,0.00004303364,0.00003143398,0.00001396663,0.9982539,0.00003921099,0.00004873924,0.0009843319],"study_design_scores_gemma":[0.00002447809,0.0005269923,0.04341815,0.00001912321,0.00004342039,0.0003596206,0.0001383049,0.000281984,0.9518718,0.0001113226,0.003187881,0.00001686858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832262,0.004564538,0.005357076,0.000360455,0.0001133385,0.00007321796,0.003608497,0.0003027498,0.002393894],"genre_scores_gemma":[0.9686233,0.005116291,0.009847854,0.0006793885,0.00005467108,0.0004215009,0.004363367,0.0001991046,0.01069457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001819165,"threshold_uncertainty_score":0.00421834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08606194300456237,"score_gpt":0.3139869007405889,"score_spread":0.2279249577360265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}