{"id":"W4290803877","doi":"10.1101/2022.08.08.503262","title":"Adaptive radioresistance of Enterohemorrhagic <i>Escherichia coli</i> O157:H7 results in genomic loss of shiga toxin-encoding prophages","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Génome Québec; Natural Sciences and Engineering Research Council of Canada; Mitacs; McGill University","keywords":"Lysogen; Prophage; Escherichia coli; Lysogenic cycle; Shiga toxin; Microbiology; Biology; STX2; Gene; Strain (injury); Bacteriophage; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010113,0.000349288,0.0002653484,0.0001718877,0.0001194428,0.0002922773,0.0002733748,0.0003468402,0.0009745943],"category_scores_gemma":[0.0002117846,0.0001100439,0.0002854143,0.0001723785,0.0001642279,0.00014297,0.0003314998,0.0005387086,0.0002443959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695885,"about_ca_system_score_gemma":0.0001320923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008072336,"about_ca_topic_score_gemma":0.0006169378,"domain_scores_codex":[0.9997665,0.00004220933,0.00002987056,0.00004346074,0.00005361928,0.00006430406],"domain_scores_gemma":[0.9997815,0.00004294768,0.00006286502,0.00003941048,0.00003406295,0.00003922376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007204471,0.00003731657,0.0007177044,0.00001228566,0.0000044626,0.00004062773,0.00001603087,0.00002207712,0.9986292,0.00001406595,0.00001333598,0.000420986],"study_design_scores_gemma":[0.00001617264,0.001243499,0.06529721,0.00001174534,0.00002685706,0.0007431856,0.0001842411,0.0006600143,0.9309164,0.00002674601,0.0008647973,0.000009004273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989698,0.0001212327,0.0004335277,0.00002365467,0.000004465323,0.00001330634,0.0001385694,0.00001522851,0.0002802716],"genre_scores_gemma":[0.9977799,0.0001016607,0.0007543871,0.00004159428,0.000003558329,0.00001967289,0.0006481485,0.00001622805,0.0006348831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009745943,"threshold_uncertainty_score":0.003260374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01473599883512836,"score_gpt":0.2374277437544767,"score_spread":0.2226917449193484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}