{"id":"W4290830384","doi":"10.1136/jnnp-2022-abn2.232","title":"188 SUNFISH 3-year efficacy and safety of risdiplam in types 2 and 3 SMA","year":2022,"lang":"en","type":"article","venue":"Journal of Neurology Neurosurgery & Psychiatry","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"SMA*; Medicine; Placebo; Spinal muscular atrophy; Population; Clinical trial; Motor function; Physical therapy; Internal medicine; Pediatrics; Physical medicine and rehabilitation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009340655,0.0004876569,0.001761419,0.0002983709,0.0002995832,0.0004471988,0.0004447274,0.0008028673,0.003186884],"category_scores_gemma":[0.0006610309,0.0002015878,0.001465927,0.000211869,0.0002835328,0.000485435,0.0001990679,0.001539763,0.0006210263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004531723,"about_ca_system_score_gemma":0.000462451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007749367,"about_ca_topic_score_gemma":0.001898323,"domain_scores_codex":[0.9996642,0.00009848586,0.00003769224,0.00005349321,0.00005751284,0.0000886522],"domain_scores_gemma":[0.9994899,0.00008016134,0.0001451731,0.00005286451,0.00008650968,0.0001454513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6715124,0.0307502,0.01368384,0.001248102,0.002275549,0.0005241074,0.0002435738,0.001445583,0.0435981,0.0001278274,0.004250383,0.2303404],"study_design_scores_gemma":[0.08739779,0.7885509,0.1046729,0.0001462233,0.00144954,0.0005520362,0.0001101415,0.001140114,0.01083971,0.0001711075,0.004905156,0.00006438523],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919446,0.004866159,0.000237393,0.0001282967,0.00009223006,0.0002643284,0.0009922032,0.0000805263,0.001394266],"genre_scores_gemma":[0.9940715,0.001574577,0.0002542707,0.0002618245,0.00008873019,0.000290861,0.001652702,0.00001272029,0.001792657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003186884,"threshold_uncertainty_score":0.01066118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01071879857524039,"score_gpt":0.2666357938498909,"score_spread":0.2559169952746505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}