{"id":"W4290830471","doi":"10.1136/jnnp-2022-abn2.231","title":"187 SUNFISH Part 2: 24-month efficacy of risdiplam compared with external control comparators","year":2022,"lang":"en","type":"article","venue":"Journal of Neurology Neurosurgery & Psychiatry","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"SMA*; Placebo; Medicine; Spinal muscular atrophy; Population; Motor function; Internal medicine; Physical therapy; Physical medicine and rehabilitation; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007051679,0.0003225911,0.001215386,0.0005752679,0.0002296836,0.00001997912,0.0004462504,0.00008500549,0.0003714002],"category_scores_gemma":[0.0001164211,0.0002708631,0.0005858366,0.0005744174,0.000363832,0.0000775824,0.0001073541,0.001763584,0.000004758958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001904118,"about_ca_system_score_gemma":0.0007641341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006946225,"about_ca_topic_score_gemma":0.000006019407,"domain_scores_codex":[0.9955305,0.000921303,0.001276322,0.0004332277,0.001251736,0.0005869385],"domain_scores_gemma":[0.997184,0.000487789,0.001093245,0.0005639946,0.0002713184,0.0003996271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02001769,0.002786942,0.9336143,0.0000742299,0.0003574457,0.001749974,0.00006053501,0.002834875,0.006299192,0.00004514294,0.03173445,0.0004252658],"study_design_scores_gemma":[0.01794228,0.01154814,0.9045779,0.00007388135,0.0005625703,0.01440266,0.0001031129,0.0003523555,0.0003753081,0.0000746737,0.04968117,0.0003059864],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874386,0.00159669,0.0001186338,0.006664798,0.003385242,0.0004936102,0.00002752899,0.0000258817,0.0002489683],"genre_scores_gemma":[0.9930081,0.0001459151,0.0001128873,0.006165212,0.0003905653,0.00001682248,0.000004828643,0.000069991,0.00008565948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02903639,"threshold_uncertainty_score":0.9999744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01715619347231028,"score_gpt":0.2714304271336868,"score_spread":0.2542742336613765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}