{"id":"W4291000611","doi":"10.1093/asj/sjac214","title":"Commentary on: Safety, Pharmacodynamic Response, and Treatment Satisfaction With Onabotulinumtoxin A 40 U, 60 U and 80 U in Subjects With Moderate to Severe Dynamic Glabellar Lines","year":2022,"lang":"en","type":"letter","venue":"Aesthetic Surgery Journal","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Dosing; Ptosis; Pharmacodynamics; Patient satisfaction; Facial rejuvenation; Surgery; Internal medicine; Pharmacokinetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003307714,0.001469793,0.001829096,0.001103401,0.002544444,0.002188262,0.003762406,0.03548297,0.01557161],"category_scores_gemma":[0.02450339,0.0008425837,0.001824826,0.0008860282,0.001864444,0.002192427,0.001183723,0.02605144,0.01124751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004326684,"about_ca_system_score_gemma":0.003530875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01140355,"about_ca_topic_score_gemma":0.01222443,"domain_scores_codex":[0.9975987,0.0006287722,0.0003251521,0.0003419844,0.0009071054,0.0001982225],"domain_scores_gemma":[0.9854853,0.008066424,0.0005888527,0.000327694,0.004430491,0.001101316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007460746,0.00001316351,0.00007105873,0.00005208808,0.0000080849,0.0001147742,0.00002409115,0.00001539531,0.00005583835,0.0001957517,0.9969265,0.002448558],"study_design_scores_gemma":[0.0006001906,0.0001800065,0.001508613,0.001044274,0.00009160664,0.0007310034,0.0003804331,0.0004213908,0.0004847516,0.003572106,0.9908859,0.00009964226],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004230443,0.001446702,0.0001541283,0.8122451,0.1825536,0.00007300692,0.0005173743,0.0001379769,0.002448986],"genre_scores_gemma":[0.002614601,0.001069058,0.0002323019,0.8413373,0.1470975,0.0001289671,0.00013504,0.00005271856,0.007332557],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03548297,"threshold_uncertainty_score":0.05209225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01347118209689238,"score_gpt":0.2480851453786367,"score_spread":0.2346139632817443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}