{"id":"W4291006623","doi":"10.1371/journal.ppat.1010718","title":"Viral-mediated activation and inhibition of programmed cell death","year":2022,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"University of Guelph; Cancer Research Institute","keywords":"Pyroptosis; Necroptosis; Programmed cell death; Biology; Viral pathogenesis; Viral replication; Apoptosis; Virus; Immunity; Intracellular; Autophagy; Virology; Cell biology; Immune system; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001801772,0.0002970852,0.0009561175,0.0002726754,0.0001166933,0.000009353375,0.0001162636,0.000394823,0.0008858828],"category_scores_gemma":[0.000164813,0.0002514637,0.000236731,0.0001643706,0.00009345886,0.00004825308,0.0001466842,0.0004760949,0.0001144355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007577706,"about_ca_system_score_gemma":0.0001477854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001067721,"about_ca_topic_score_gemma":5.238371e-7,"domain_scores_codex":[0.9981918,0.0006656707,0.0005122466,0.0003193002,0.00004833028,0.0002626211],"domain_scores_gemma":[0.9988945,0.0003573868,0.0004373135,0.0002537126,0.00003991656,0.00001723498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001824861,0.000733635,0.00001235136,0.008918615,0.0005158156,0.00001397753,0.0003622206,3.23625e-8,0.2896086,0.0001129322,0.0003634864,0.6991759],"study_design_scores_gemma":[0.000413685,0.0004413439,0.00001038878,0.001415561,0.0005000253,0.00002894066,0.00006941133,3.541355e-7,0.03250414,0.000006497197,0.9643551,0.0002545288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009804378,0.9881284,0.000007154983,0.000006488354,0.0001714717,0.0008693014,0.0003414764,0.00006375174,0.0006076302],"genre_scores_gemma":[0.002226207,0.9935929,0.00003113693,0.00002078804,0.00001532495,0.0002531282,0.002846429,0.0000455128,0.0009685933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9639916,"threshold_uncertainty_score":0.9999937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04963926402825448,"score_gpt":0.2756812271891689,"score_spread":0.2260419631609144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}