{"id":"W4291019073","doi":"10.4314/ejhs.v32i4.5","title":"Screening of BRCA1 (c.5177_5180delGAAA rs80357867 and c.4986+6T>C rs80358086) and the BRCA2 (c.6445_6446delAT rs80359592) genes for breast cancer prevention in Burkina Faso","year":2022,"lang":"en","type":"article","venue":"Ethiopian Journal of Health Sciences","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas University","funders":"","keywords":"Breast cancer; Medicine; Internal medicine; Odds ratio; Genotype; Confidence interval; Oncology; Cancer; Gastroenterology; Case-control study; Allele; Family history; Population; Gynecology; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005030019,0.0001371334,0.000327414,0.00018781,0.0006443936,0.00004276995,0.0003706319,0.00006340064,0.00002522645],"category_scores_gemma":[0.00008564076,0.0001042876,0.00009492489,0.0003463852,0.0006769518,0.00002883351,0.0001745973,0.0002452974,5.185053e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000769144,"about_ca_system_score_gemma":0.00115382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001950106,"about_ca_topic_score_gemma":0.0003593944,"domain_scores_codex":[0.9978367,0.000433167,0.0007185053,0.000304808,0.0004030664,0.0003037705],"domain_scores_gemma":[0.9986566,0.0001245207,0.0008179948,0.0001510595,0.0001633696,0.0000864765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003300073,0.0003582397,0.1006807,0.0009982637,0.0004558404,0.00001107602,0.01317602,0.05377191,0.03335369,0.009148366,0.004132578,0.7806133],"study_design_scores_gemma":[0.05787427,0.01946957,0.6116234,0.003136227,0.0006021268,0.007544922,0.0619159,0.02891272,0.0264466,0.03341864,0.1457828,0.003272791],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9358339,0.03843659,0.00430628,0.02007195,0.0006007905,0.0005905154,0.00008625843,0.000003344673,0.0000703258],"genre_scores_gemma":[0.9918244,0.002799808,0.00434923,0.0006503385,0.0002000769,0.00004813885,0.000003595439,0.00001316838,0.0001111822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7773405,"threshold_uncertainty_score":0.4956219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904995770536313,"score_gpt":0.3448899318192242,"score_spread":0.3158399741138611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}