{"id":"W4291019073","doi":"10.4314/ejhs.v32i4.5","title":"Screening of BRCA1 (c.5177_5180delGAAA rs80357867 and c.4986+6T>C rs80358086) and the BRCA2 (c.6445_6446delAT rs80359592) genes for breast cancer prevention in Burkina Faso","year":2022,"lang":"en","type":"article","venue":"Ethiopian Journal of Health Sciences","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas University","funders":"","keywords":"Breast cancer; Medicine; Internal medicine; Odds ratio; Genotype; Confidence interval; Oncology; Cancer; Gastroenterology; Case-control study; Allele; Family history; Population; Gynecology; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008775481,0.0002473241,0.000224356,0.000720713,0.0005703494,0.0003950864,0.0002538314,0.0003766449,0.001409735],"category_scores_gemma":[0.001394909,0.0001712239,0.0001401843,0.000589263,0.0002658034,0.0002301165,0.0002386268,0.0001726129,0.0001509337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004135894,"about_ca_system_score_gemma":0.0002937974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007451108,"about_ca_topic_score_gemma":0.009913277,"domain_scores_codex":[0.9995527,0.0001534505,0.0000486493,0.0001248862,0.00006844718,0.00005200943],"domain_scores_gemma":[0.999472,0.0001315752,0.000247708,0.00002799264,0.00007354407,0.00004730509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001184414,0.00007029298,0.9908071,0.00004288707,0.00003372739,0.0003582744,0.0003820371,0.00003013997,0.00299183,0.00003754766,0.00008922413,0.00503865],"study_design_scores_gemma":[0.00003589505,0.0004072452,0.992729,0.0001001267,0.0001209561,0.002642005,0.0008337867,0.0002289743,0.00144927,0.0001392821,0.001305981,0.000007373363],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998463,0.0009308787,0.000139858,0.00005526443,0.000003213008,0.00001821679,0.0001074168,0.000002209165,0.0002799481],"genre_scores_gemma":[0.9990329,0.0003982529,0.0002374653,0.00004763807,0.000004453981,0.00001315442,0.0000871184,7.111162e-7,0.0001785138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007451108,"threshold_uncertainty_score":0.01481551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904995770536313,"score_gpt":0.3448899318192242,"score_spread":0.3158399741138611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}