{"id":"W4291019371","doi":"10.1161/hypertensionaha.122.19307","title":"Selective IgA Deficiency in Spontaneously Hypertensive Rats With Gut Dysbiosis","year":2022,"lang":"en","type":"article","venue":"Hypertension","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Crohn's and Colitis Foundation","keywords":"Dysbiosis; Immunoglobulin A; Immunology; Gut flora; Immune system; Flagellin; Antibody; Immunoglobulin G; Biology; Internal medicine; Endocrinology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002016105,0.0005129466,0.0003819637,0.0006120781,0.0002544473,0.000202608,0.0001290226,0.0003180199,0.002268184],"category_scores_gemma":[0.0001905719,0.0002370632,0.0003115809,0.0001921361,0.000356414,0.0002511451,0.0002719583,0.0007493665,0.0002597396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001982116,"about_ca_system_score_gemma":0.0002116344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005705392,"about_ca_topic_score_gemma":0.0008288165,"domain_scores_codex":[0.9998653,0.00002498785,0.0000152327,0.0000307411,0.00002676374,0.00003691984],"domain_scores_gemma":[0.9995885,0.00002492052,0.0001479178,0.00003688164,0.00002833226,0.0001734578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001666975,0.000369463,0.006946714,0.00008196278,0.0000359313,0.000641506,0.00007964594,0.00004749309,0.9858685,0.0001123426,0.0001238744,0.004025581],"study_design_scores_gemma":[0.0003286597,0.01197737,0.3864548,0.00007478201,0.0003643355,0.005276775,0.000622516,0.002728258,0.5882502,0.0005504325,0.003317827,0.00005403453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978831,0.000377226,0.000906784,0.0000893562,0.00002981526,0.00002169692,0.0001571814,0.00007836112,0.000456453],"genre_scores_gemma":[0.9969441,0.0004526601,0.001083561,0.00006686313,0.00002267433,0.00004730782,0.0002181157,0.00001770256,0.001146916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002268184,"threshold_uncertainty_score":0.00758785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009497816594922296,"score_gpt":0.2082654233323086,"score_spread":0.1987676067373863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}