{"id":"W4291019371","doi":"10.1161/hypertensionaha.122.19307","title":"Selective IgA Deficiency in Spontaneously Hypertensive Rats With Gut Dysbiosis","year":2022,"lang":"en","type":"article","venue":"Hypertension","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Crohn's and Colitis Foundation","keywords":"Dysbiosis; Immunoglobulin A; Immunology; Gut flora; Immune system; Flagellin; Antibody; Immunoglobulin G; Biology; Internal medicine; Endocrinology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014109,0.0001724944,0.0002232476,0.00009767438,0.0002728576,0.00001058858,0.000145147,0.00008247534,0.00003122651],"category_scores_gemma":[0.00002817202,0.0001491035,0.00005014849,0.0002804908,0.00004717177,0.00000343485,0.000151878,0.0002180939,0.00001344595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007233591,"about_ca_system_score_gemma":0.0001957479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002079944,"about_ca_topic_score_gemma":0.0004077325,"domain_scores_codex":[0.9986873,0.0001121064,0.000178437,0.0004899632,0.0001635032,0.0003686767],"domain_scores_gemma":[0.999431,0.00001171292,0.00006626067,0.0002871412,0.000131352,0.00007258845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003671108,0.0001772009,0.002189293,0.00001100693,0.00001115502,0.0002490844,0.0001263155,0.0001777281,0.989297,0.00001791973,0.006992813,0.0003833603],"study_design_scores_gemma":[0.01175098,0.01830815,0.2701542,0.0002160981,0.0002612496,0.03643897,0.009003686,0.001465473,0.4518573,0.0002113707,0.1965231,0.003809443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972166,0.0008458892,0.0000208424,0.0004426138,0.0001248115,0.000302873,0.00001787597,0.00001724245,0.00101119],"genre_scores_gemma":[0.9959652,0.00009156882,0.0003253758,0.00303182,0.00004777055,0.00003590163,0.0001133893,0.00003032689,0.0003586346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5374398,"threshold_uncertainty_score":0.6080265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009497816594922296,"score_gpt":0.2082654233323086,"score_spread":0.1987676067373863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}