{"id":"W4291111229","doi":"10.1155/2022/5431666","title":"A Model of Intracellular Persistence of Pseudomonas aeruginosa in Airway Epithelial Cells","year":2022,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; McGill University; McGill University Health Centre","funders":"Cystic Fibrosis Canada; McGill University; Deutscher Akademischer Austauschdienst; McGill University Health Centre; Cystic Fibrosis Foundation","keywords":"Intracellular; Biology; Pseudomonas aeruginosa; Microbiology; Intracellular parasite; Internalization; Pathogen; Extracellular; Cystic fibrosis; Flow cytometry; Cell culture; Multiplicity of infection; Cell; Immunology; Cell biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002404667,0.000760854,0.0008383983,0.0005278619,0.0004857453,0.0007575881,0.001267537,0.001577188,0.0009514889],"category_scores_gemma":[0.0001623839,0.0003429822,0.0006651857,0.0005479961,0.0004237084,0.0005269359,0.000706583,0.001296248,0.0006849079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007998427,"about_ca_system_score_gemma":0.0005343395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002841665,"about_ca_topic_score_gemma":0.001735377,"domain_scores_codex":[0.9996359,0.00006099588,0.00002699927,0.0001000857,0.0001252491,0.00005070151],"domain_scores_gemma":[0.9998009,0.00004375969,0.00004875,0.00003021408,0.00004078066,0.00003566171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00009760498,0.0001003725,0.0002206689,0.000177371,0.00001104194,0.000330939,0.00007789351,0.009365951,0.9828144,0.005297619,0.0001697555,0.001336484],"study_design_scores_gemma":[0.0002505262,0.003682037,0.005107511,0.0001169473,0.0001455808,0.002062982,0.0003393279,0.3741971,0.5610713,0.009200357,0.04369029,0.0001358695],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8263199,0.008066337,0.1420922,0.002207624,0.0004410024,0.0004465077,0.003797727,0.0003713738,0.01625724],"genre_scores_gemma":[0.9281446,0.004741391,0.05428836,0.0003140093,0.00007776933,0.0007621828,0.001654463,0.00004691708,0.009970302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002841665,"threshold_uncertainty_score":0.005803347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246824974871324,"score_gpt":0.1943809671612225,"score_spread":0.1819127174125093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}