{"id":"W4291214311","doi":"10.1007/s42399-022-01265-3","title":"Study Design Solutions for Adjuvant and Maintenance Therapy in Cancer: Ovarian Cancer as an Example","year":2022,"lang":"en","type":"article","venue":"SN Comprehensive Clinical Medicine","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Cancer Care Ontario; McMaster University; Queen's University; Impact; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Randomized controlled trial; Guideline; Soundness; Maintenance therapy; Adjuvant therapy; Ovarian cancer; Research design; Cancer; Oncology; Medical physics; Internal medicine; Chemotherapy; Computer science; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1024123,0.001965702,0.001829566,0.001548451,0.00200189,0.002787154,0.002337893,0.004629245,0.02212862],"category_scores_gemma":[0.1366014,0.001084073,0.004034579,0.001108049,0.00203978,0.001909422,0.003070206,0.003163855,0.003560345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003154702,"about_ca_system_score_gemma":0.01425207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000993983,"about_ca_topic_score_gemma":0.001592279,"domain_scores_codex":[0.8637571,0.119801,0.006409663,0.004089643,0.003691438,0.002251198],"domain_scores_gemma":[0.8940647,0.07135629,0.007434001,0.01131157,0.01248895,0.003344439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.04711469,0.005137404,0.02296839,0.02455072,0.005287873,0.0004001596,0.003498472,0.0181501,0.00405278,0.1519476,0.02916164,0.6877303],"study_design_scores_gemma":[0.08202349,0.1207562,0.01763935,0.01597555,0.01457505,0.0008456475,0.006139776,0.09620905,0.02509421,0.3063457,0.3138862,0.000509811],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.05268385,0.005367455,0.5927971,0.01325943,0.005903665,0.3033248,0.004021211,0.0009131083,0.02172937],"genre_scores_gemma":[0.132495,0.000994256,0.4464603,0.005036691,0.0003953632,0.4091713,0.0006408461,0.000121968,0.004684263],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.1024123,"threshold_uncertainty_score":0.5416144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3352415838719477,"score_gpt":0.4577303692073915,"score_spread":0.1224887853354438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}