{"id":"W4291214311","doi":"10.1007/s42399-022-01265-3","title":"Study Design Solutions for Adjuvant and Maintenance Therapy in Cancer: Ovarian Cancer as an Example","year":2022,"lang":"en","type":"article","venue":"SN Comprehensive Clinical Medicine","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Cancer Care Ontario; McMaster University; Queen's University; Impact; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Randomized controlled trial; Guideline; Soundness; Maintenance therapy; Adjuvant therapy; Ovarian cancer; Research design; Cancer; Oncology; Medical physics; Internal medicine; Chemotherapy; Computer science; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001109289,0.0002900531,0.001078989,0.0001555211,0.0003582311,0.00001032876,0.0001605597,0.000071795,0.0008540985],"category_scores_gemma":[0.0001837006,0.0002185794,0.0001047666,0.0003719005,0.0002863314,0.00005895544,0.0001368114,0.0004636021,0.000002295262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003170149,"about_ca_system_score_gemma":0.0004815008,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01295658,"about_ca_topic_score_gemma":0.001098866,"domain_scores_codex":[0.9967808,0.0005326496,0.0008483189,0.0008972448,0.000394987,0.0005460196],"domain_scores_gemma":[0.9969872,0.0015916,0.0002173374,0.000534387,0.0003080687,0.0003614036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008374755,0.01136969,0.5291836,0.0001012455,0.001449504,0.0007737156,0.00713978,0.0007511726,0.0003537912,0.00217626,0.02910421,0.4092223],"study_design_scores_gemma":[0.04820035,0.03418694,0.8423379,0.0003272928,0.0005005256,0.00005807396,0.00794592,0.001258152,0.0000194917,0.001924611,0.06289819,0.0003425596],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9368047,0.01631412,0.0005913363,0.03691391,0.001934136,0.007103445,0.0001131028,0.00008295068,0.0001423427],"genre_scores_gemma":[0.9756054,0.008142242,0.000614576,0.009771504,0.0007572069,0.004817891,0.00004426312,0.00004984131,0.0001970304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4088797,"threshold_uncertainty_score":0.9936162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3352415838719477,"score_gpt":0.4577303692073915,"score_spread":0.1224887853354438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}