{"id":"W4291512777","doi":"10.3390/pathogens11080908","title":"Legionella pneumophila Infection of Human Macrophages Retains Golgi Structure but Reduces O-Glycans","year":2022,"lang":"en","type":"article","venue":"Pathogens","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Toronto Scarborough; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Golgi apparatus; Legionella pneumophila; Biology; Cell biology; Microbiology; Glycosylation; Macrophage; U937 cell; Endoplasmic reticulum; Bacteria; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001724308,0.0001498305,0.0001631936,0.00009311285,0.0004126048,0.00001621548,0.0002290702,0.00009340383,0.00009100762],"category_scores_gemma":[0.00003046633,0.0001490212,0.0001320254,0.0002018936,0.0001309025,0.000003475096,0.000296173,0.0002114611,0.000002441297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003199455,"about_ca_system_score_gemma":0.00009115702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001656403,"about_ca_topic_score_gemma":0.00005721271,"domain_scores_codex":[0.9987071,0.0001498831,0.0002152268,0.0003681194,0.0002791406,0.0002805341],"domain_scores_gemma":[0.9993603,0.00000800221,0.0001126074,0.0003534817,0.0000868596,0.00007870702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003874341,0.00006349796,0.006878354,0.00002455026,0.00004258899,0.00002208384,0.0001212159,0.0002180384,0.9905727,0.0001303214,0.001381566,0.0005063334],"study_design_scores_gemma":[0.0003903484,0.000596312,0.008079219,0.000005357651,0.00002666099,0.00009689078,0.0002375302,0.00002924323,0.9759268,0.0002400425,0.01414182,0.0002298319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974596,0.0004782463,0.00002077994,0.0001537535,0.0001841256,0.000178523,0.0003187005,0.00001565641,0.001190606],"genre_scores_gemma":[0.997521,0.0001724309,0.00004244144,0.00006976067,0.0002906373,0.00002671806,0.0003241491,0.00003014425,0.001522655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01464597,"threshold_uncertainty_score":0.6076908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01476199658806348,"score_gpt":0.2712032649185355,"score_spread":0.256441268330472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}