{"id":"W4291512777","doi":"10.3390/pathogens11080908","title":"Legionella pneumophila Infection of Human Macrophages Retains Golgi Structure but Reduces O-Glycans","year":2022,"lang":"en","type":"article","venue":"Pathogens","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Toronto Scarborough; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Golgi apparatus; Legionella pneumophila; Biology; Cell biology; Microbiology; Glycosylation; Macrophage; U937 cell; Endoplasmic reticulum; Bacteria; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001395657,0.0003020292,0.0002210776,0.0001185802,0.0001317012,0.0002574921,0.00009476351,0.0002776307,0.0007285939],"category_scores_gemma":[0.00009717044,0.0001175845,0.0002378302,0.0001248323,0.0001203103,0.0001819911,0.000159462,0.0003046508,0.0003475575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001908776,"about_ca_system_score_gemma":0.0001501177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007134958,"about_ca_topic_score_gemma":0.0007996369,"domain_scores_codex":[0.999881,0.00002203547,0.000012355,0.00002219432,0.00002572554,0.00003657354],"domain_scores_gemma":[0.9999385,0.000007701538,0.00001212866,0.00001141555,0.00001543299,0.00001490615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000908994,0.00001060539,0.0001775577,0.00001924556,0.000002317093,0.00003766592,0.00001442615,0.000009506377,0.9993379,0.00001754661,0.00001767453,0.0002646826],"study_design_scores_gemma":[0.00001789597,0.0004414467,0.01275479,0.00001251138,0.00001615531,0.0003935463,0.00008766467,0.0004871622,0.9835522,0.00003956718,0.002190842,0.000006294333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963191,0.001402481,0.0008965455,0.00008682037,0.00001739834,0.00001841357,0.0005158837,0.00003970172,0.0007036747],"genre_scores_gemma":[0.9947572,0.0008124899,0.001458901,0.00008816664,0.000006107605,0.00003625485,0.0008515986,0.00001610141,0.001973126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007285939,"threshold_uncertainty_score":0.002437413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01476199658806348,"score_gpt":0.2712032649185355,"score_spread":0.256441268330472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}