{"id":"W4291513501","doi":"10.1080/14656566.2022.2112945","title":"Colesevelam – a bile acid sequestrant for treating hypercholesterolemia and improving hyperglycemia","year":2022,"lang":"en","type":"article","venue":"Expert Opinion on Pharmacotherapy","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Medicine; Bile acid; Adverse effect; Internal medicine; Cholesterol; Diabetes mellitus; Glycemic; Pharmacology; Endocrinology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005119886,0.0003897326,0.0007631202,0.0008517579,0.0001561191,0.0009437258,0.0005521762,0.001422478,0.005848208],"category_scores_gemma":[0.001048534,0.0001196051,0.000684611,0.0004200646,0.0002858173,0.0005678737,0.0003710747,0.001875704,0.00284487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004231008,"about_ca_system_score_gemma":0.0004252412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006828874,"about_ca_topic_score_gemma":0.001552959,"domain_scores_codex":[0.9995911,0.0001061738,0.00003942718,0.00005314014,0.0001648457,0.00004542275],"domain_scores_gemma":[0.9996456,0.0001032848,0.00007650613,0.00001034038,0.0001256554,0.00003869244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004312173,0.0001337368,0.0005265268,0.00679872,0.0003176473,0.0005139306,0.00005671384,0.0003848829,0.007224852,0.004756628,0.1433555,0.8354996],"study_design_scores_gemma":[0.0004246695,0.0004473893,0.00164952,0.003425266,0.0003107858,0.002538399,0.00005790962,0.0005210414,0.003075517,0.003169734,0.9843472,0.00003253566],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.002146574,0.965618,0.001865145,0.01502857,0.003169373,0.00006469066,0.0002501006,0.0001074699,0.0117502],"genre_scores_gemma":[0.02152407,0.9514908,0.002560525,0.01001621,0.004059977,0.00008944378,0.0005658283,0.00002622692,0.00966692],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005848208,"threshold_uncertainty_score":0.01956415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03166872976710378,"score_gpt":0.344601104480753,"score_spread":0.3129323747136493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}