{"id":"W4291618406","doi":"10.1371/journal.ppat.1010764","title":"Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ohio State University","keywords":"Microbiology; Bordetella pertussis; Biology; Pathogen; Escherichia coli; Antimicrobial peptides; Antimicrobial; Bacteria; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903175,0.0002278859,0.0003898999,0.0001047729,0.000711494,0.0000344299,0.00009241186,0.0001751037,0.0005489361],"category_scores_gemma":[0.0001191398,0.0002310897,0.00007019151,0.000199272,0.0001724759,0.00009587972,0.0002924964,0.0002812131,0.00001423076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003755717,"about_ca_system_score_gemma":0.00009642056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000504226,"about_ca_topic_score_gemma":0.0000991775,"domain_scores_codex":[0.9984877,0.0003640105,0.0003750644,0.0004365732,0.00003880256,0.0002978375],"domain_scores_gemma":[0.9992824,0.0001755712,0.0001887957,0.0002311927,0.00007177077,0.00005029649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000339599,0.0001676702,0.02957156,0.00004570872,0.0001874293,0.000007426592,0.001297313,0.000002651274,0.9660765,0.00003984443,0.001820041,0.0004442353],"study_design_scores_gemma":[0.002808922,0.001628773,0.01804138,0.00008055889,0.0004310594,0.0003442353,0.002848163,0.00002314207,0.9435068,0.00007310019,0.02939642,0.0008174412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959032,0.002712289,0.000006794466,0.0001824843,0.0004050662,0.0002540136,0.0003924044,0.00006187228,0.00008188248],"genre_scores_gemma":[0.9986812,0.0002098927,0.0001263764,0.0002827148,0.00003721232,0.00003305851,0.00006606133,0.00003226312,0.0005311521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02757638,"threshold_uncertainty_score":0.9423566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159329347110435,"score_gpt":0.2198995631494133,"score_spread":0.2083062696783089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}