{"id":"W4291802906","doi":"10.1089/cell.2022.0076","title":"An Improved Method to Generate Human Induced Astrocytes","year":2022,"lang":"en","type":"article","venue":"Cellular Reprogramming","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biology; Astrocyte; Function (biology); Neuroscience; Cell biology; Computational biology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001260924,0.0008635433,0.0005502625,0.0009643399,0.0005548774,0.0005850916,0.0006674887,0.0009485947,0.004970957],"category_scores_gemma":[0.0006527288,0.0003779633,0.0008222829,0.0006559454,0.0002494436,0.0003240062,0.0005602351,0.002201168,0.004389608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001614737,"about_ca_system_score_gemma":0.0006367469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008164085,"about_ca_topic_score_gemma":0.002307507,"domain_scores_codex":[0.9992099,0.000141296,0.0001375611,0.0001405054,0.0002969408,0.00007376287],"domain_scores_gemma":[0.999563,0.00009251368,0.0000345407,0.0001304026,0.0001270181,0.00005248923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008341783,0.0001164419,0.0001822517,0.0002116343,0.00001762933,0.0003119204,0.00008927767,0.000158145,0.9770577,0.001010094,0.001490595,0.01927091],"study_design_scores_gemma":[0.00009315009,0.0003647582,0.002343894,0.00006996195,0.0001111313,0.002280191,0.00004428777,0.001685027,0.8651252,0.0008655568,0.1269596,0.00005720151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06342018,0.006902231,0.8978159,0.0009888173,0.002201638,0.003248031,0.00429764,0.002706025,0.01841956],"genre_scores_gemma":[0.1677463,0.009831605,0.771808,0.0008770037,0.0002577587,0.005135522,0.01111578,0.001047829,0.03218027],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.004970957,"threshold_uncertainty_score":0.01662952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05722640390332868,"score_gpt":0.3270592124660516,"score_spread":0.2698328085627229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}