{"id":"W4291802906","doi":"10.1089/cell.2022.0076","title":"An Improved Method to Generate Human Induced Astrocytes","year":2022,"lang":"en","type":"article","venue":"Cellular Reprogramming","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biology; Astrocyte; Function (biology); Neuroscience; Cell biology; Computational biology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0007602184,0.0002131682,0.0001880543,0.0002211323,0.001305032,0.0002697399,0.0005150192,0.00003566535,0.0003309819],"category_scores_gemma":[0.0001087576,0.0002410416,0.00009211702,0.0006312286,0.00001575699,0.0001973889,0.000266681,0.0003338991,0.00004952119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005688065,"about_ca_system_score_gemma":0.00003861952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001493193,"about_ca_topic_score_gemma":0.000002307595,"domain_scores_codex":[0.9968862,0.0008339527,0.000380292,0.001030042,0.0004379804,0.0004315214],"domain_scores_gemma":[0.9987416,0.00004723338,0.0001579808,0.000746094,0.00003937123,0.0002677342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001729631,0.00008973085,0.000007097398,0.000003826357,0.0000015366,0.00005748364,0.0002662441,0.001007717,0.9750741,0.00368612,0.00002249273,0.01976634],"study_design_scores_gemma":[0.0002892485,0.0006113675,0.000005153287,0.000001142353,0.000007268168,0.0000287057,0.0001180856,0.01149931,0.9745359,0.0001071384,0.01254685,0.0002498745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9165142,0.000004951883,0.0815818,0.0001740377,0.0003876185,0.0006514319,0.000005195278,0.0004723965,0.000208376],"genre_scores_gemma":[0.9724697,3.503112e-7,0.02441025,0.001623231,0.0001754246,0.0003168489,0.00002102297,0.00006612382,0.0009170643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05717155,"threshold_uncertainty_score":0.9999951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05722640390332868,"score_gpt":0.3270592124660516,"score_spread":0.2698328085627229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}