{"id":"W4291825280","doi":"10.1002/alz.12763","title":"Differential diagnosis of amnestic dementia patients based on an FDG‐PET signature of autopsy‐confirmed LATE‐NC","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Instituto de Salud Carlos III; Canadian Institutes of Health Research; National Institutes of Health; Genentech; U.S. National Library of Medicine; National Institute of Neurological Disorders and Stroke; IXICO; H. Lundbeck A/S; Knut och Alice Wallenbergs Stiftelse; Servier; Vetenskapsrådet; Eisai; Northern California Institute for Research and Education; Wallenberg Centre for Molecular and Translational Medicine; BioClinica; Biogen; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; European Regional Development Fund; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Autopsy; Dementia; Medicine; Pathology; Positron emission tomography; Differential diagnosis; Biomarker; Internal medicine; Disease; Psychology; Oncology; Radiology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004995348,0.0004777414,0.0003113197,0.0007513565,0.0002624399,0.0004856384,0.0002655091,0.0003039525,0.001018504],"category_scores_gemma":[0.001562953,0.0001407397,0.000153143,0.0003014489,0.0002151656,0.0002484081,0.0002866335,0.0001876193,0.0002661328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000164223,"about_ca_system_score_gemma":0.000197678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006962632,"about_ca_topic_score_gemma":0.00148294,"domain_scores_codex":[0.9998741,0.00002718995,0.00002459129,0.0000289903,0.00002421662,0.00002092055],"domain_scores_gemma":[0.9994557,0.0001169463,0.0001803381,0.00004483879,0.00006942954,0.0001325714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005028986,0.00004765092,0.9878541,0.00001352215,0.00002269844,0.003833556,0.0001123574,0.00005751011,0.004183499,0.0000245118,0.00007094829,0.003276831],"study_design_scores_gemma":[0.00003357266,0.0003085145,0.9744795,0.00001711087,0.00004533815,0.02268067,0.0002098359,0.0005054305,0.001372047,0.0001063464,0.0002346862,0.000007094435],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994036,0.0001333844,0.00009279262,0.000009709666,0.000002770101,0.000008765063,0.00003971911,0.000004304051,0.0003049554],"genre_scores_gemma":[0.9995777,0.0000516242,0.0001781375,0.00001299647,0.000007595596,0.000004666641,0.00009831433,9.690945e-7,0.00006787167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001018504,"threshold_uncertainty_score":0.00340718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840253544898075,"score_gpt":0.2877743784825489,"score_spread":0.2693718430335681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}