{"id":"W4292059246","doi":"10.3389/fimmu.2022.871080","title":"Cranberry polyphenols and agave agavins impact gut immune response and microbiota composition while improving gut barrier function, inflammation, and glucose metabolism in mice fed an obesogenic diet","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université Laval","funders":"Consejo Nacional de Ciencia y Tecnología; Ministère de l'Économie, de l’Innovation et des Exportations du Québec; Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Akkermansia muciniphila; Gut flora; Akkermansia; Bacteroides; Immune system; Biology; Inflammation; Butyrate; Diet-induced obese; Microbiology; Faecalibacterium prausnitzii; Endocrinology; Immunology; Biochemistry; Bacteria; Insulin resistance; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552832,0.000557057,0.000426189,0.0005751265,0.000216309,0.0002938823,0.0001908201,0.0003862493,0.0009880338],"category_scores_gemma":[0.000101878,0.0002165416,0.0003599742,0.0002094125,0.0003286491,0.0003510107,0.0002244645,0.001114732,0.0001451349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002511959,"about_ca_system_score_gemma":0.000266195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00108767,"about_ca_topic_score_gemma":0.002042221,"domain_scores_codex":[0.9998432,0.00002170287,0.00001016411,0.00003923736,0.00003470775,0.00005103515],"domain_scores_gemma":[0.9998547,0.000007457402,0.0000450689,0.00001150149,0.00001664366,0.00006464873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002456131,0.0004276895,0.0008156364,0.00006281924,0.0000198918,0.00003394931,0.00003459023,0.00004138127,0.9936202,0.00003479655,0.00003905757,0.002413766],"study_design_scores_gemma":[0.0002619286,0.01119411,0.06804919,0.00004648648,0.0002651547,0.0002539593,0.0002106485,0.001255193,0.9149688,0.0001687538,0.003295669,0.00003022796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981527,0.0007026494,0.0004446083,0.00009554678,0.00001640147,0.00001699579,0.0002357678,0.00002565948,0.0003096664],"genre_scores_gemma":[0.9931777,0.001125137,0.001846648,0.0001405904,0.00001494933,0.000067983,0.0004303788,0.000022495,0.003174182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108767,"threshold_uncertainty_score":0.003305316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004392130795809869,"score_gpt":0.2178975716678062,"score_spread":0.2135054408719963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}