{"id":"W4292087083","doi":"10.1016/j.ygeno.2022.110449","title":"Epigenomics of rats' liver and its cross-species functional annotation reveals key regulatory genes underlying short term heat-stress response","year":2022,"lang":"en","type":"article","venue":"Genomics","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Heat stress; Gene; RNA-Seq; Epigenomics; Genetics; Epigenetics; Computational biology; Transcriptome; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005715662,0.000155852,0.0003179288,0.0001608058,0.0003118037,0.00002135218,0.00008433958,0.00007358243,0.0001808163],"category_scores_gemma":[0.00004405776,0.0001707459,0.0000784897,0.0001190849,0.0001050787,0.00009887209,0.0001402286,0.0001552785,0.000005145979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753641,"about_ca_system_score_gemma":0.0002265542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008261892,"about_ca_topic_score_gemma":0.000004571401,"domain_scores_codex":[0.9987308,0.0001155223,0.0003798866,0.0002994916,0.0002526621,0.0002216714],"domain_scores_gemma":[0.9992843,0.0001066902,0.00009167106,0.0002707509,0.0001342499,0.0001123903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002637355,0.00009169031,0.02356604,0.0001178216,0.0001285063,0.00005141077,0.002838587,0.001173482,0.9644471,0.001133924,0.0003720448,0.003441989],"study_design_scores_gemma":[0.0008158808,0.0002108917,0.9225695,0.00002125371,0.0001591846,0.0001735746,0.0007475148,0.000307686,0.03823106,0.0001062755,0.03644118,0.0002160374],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830865,0.01552357,0.0001309038,0.0001653348,0.0003431411,0.0003731132,0.0002004575,0.00002804648,0.0001489007],"genre_scores_gemma":[0.9928598,0.001008024,0.0005361718,0.0002286578,0.0002253543,0.00002659361,0.000132054,0.0000367852,0.004946541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9262161,"threshold_uncertainty_score":0.6962817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06304663477939024,"score_gpt":0.2963067853108196,"score_spread":0.2332601505314293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}