{"id":"W4292102088","doi":"10.1111/imm.13563","title":"β1 Integrin induces adhesion and migration of human Th17 cells via Pyk2‐dependent activation of <scp>P2X4</scp> receptor","year":2022,"lang":"en","type":"article","venue":"Immunology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Integrin; Purinergic receptor; Apyrase; Fibronectin; Purinergic signalling; Cell adhesion; Focal adhesion; Collagen receptor; Biology; Cell migration; Chemistry; Receptor; Signal transduction; Extracellular matrix; Cell; Adenosine receptor; Biochemistry; Extracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491236,0.00009453538,0.000146341,0.0000775997,0.00008578729,0.000003601,0.000131026,0.0001184472,0.00004759302],"category_scores_gemma":[0.00005048917,0.00009459613,0.00003997304,0.00007322738,0.00006844816,0.00000573442,0.0001821326,0.0001308489,9.803107e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001326468,"about_ca_system_score_gemma":0.00003543561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002236025,"about_ca_topic_score_gemma":0.000006216313,"domain_scores_codex":[0.9992449,0.0001256482,0.0002359699,0.0001930751,0.00008848131,0.0001119124],"domain_scores_gemma":[0.9994936,0.00003265041,0.0002212358,0.0001722973,0.00006238466,0.00001785061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003704607,0.00007726027,0.0005843113,0.00001302457,0.00005123149,4.057698e-7,0.0003871413,0.00004226661,0.9964803,0.00006812097,0.001463961,0.0007949311],"study_design_scores_gemma":[0.0003470209,0.0008597236,0.001078093,0.00000808824,0.00001177426,0.000006483555,0.001030854,0.000007975003,0.9920237,0.0000905966,0.00449262,0.00004307142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997834,0.001472107,0.000235906,0.00006347227,0.0001278821,0.000107365,0.00001228769,0.000005747784,0.000141188],"genre_scores_gemma":[0.9991494,0.0001604025,0.0001029266,0.0000447577,0.00006024881,0.00001840626,0.0001675065,0.00001099985,0.0002853535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004456601,"threshold_uncertainty_score":0.3857518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01039786176872839,"score_gpt":0.2355952830149609,"score_spread":0.2251974212462325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}