{"id":"W4292115724","doi":"10.1093/jpp/rgac052","title":"γ-Terpinene complexed with β-cyclodextrin attenuates spinal neuroactivity in animals with cancer pain by Ca2+ channel block","year":2022,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Chemistry; Pharmacology; Calcium channel; Cyclodextrin; Voltage-dependent calcium channel; Hyperalgesia; Spinal cord; Calcium; Anesthesia; Medicine; Receptor; Biochemistry; Nociception","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008219931,0.000259265,0.0002373192,0.0002056216,0.00007436664,0.0001639878,0.0002023967,0.0002023338,0.001304796],"category_scores_gemma":[0.0001433376,0.00008305586,0.000201748,0.0001130542,0.0002337825,0.0001903289,0.0001173206,0.0004509705,0.0001990707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001327034,"about_ca_system_score_gemma":0.0001518444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00034708,"about_ca_topic_score_gemma":0.0003774585,"domain_scores_codex":[0.9999385,0.000008461616,0.000005979637,0.00001178837,0.00001759014,0.00001761834],"domain_scores_gemma":[0.9999261,0.00001183897,0.00002736585,0.00001062454,0.000008238028,0.00001576102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003981293,0.00007839563,0.00005976403,0.0000428251,0.000008273405,0.00002032504,0.000009895871,0.00008126032,0.9982323,0.00003185598,0.00001803338,0.001018915],"study_design_scores_gemma":[0.00004745065,0.0008475333,0.001048257,0.000007161128,0.00001620089,0.00005376022,0.0000123179,0.0006666992,0.9964233,0.00001916136,0.0008552059,0.000003096668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971099,0.0006926675,0.001316056,0.00007284054,0.00002981956,0.00003637583,0.0001120683,0.00004948777,0.0005806549],"genre_scores_gemma":[0.9950857,0.001215876,0.001714581,0.00004508269,0.00001286862,0.00005872936,0.0002091241,0.00001571712,0.001642363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001304796,"threshold_uncertainty_score":0.004365027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02316544517096258,"score_gpt":0.3205508835282099,"score_spread":0.2973854383572473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}