{"id":"W4292121216","doi":"10.1136/archdischild-2022-rcpch.321","title":"672 Carbonic Anhydrase (CA-VA) deficiency: an under recognized cause of neonatal hyperammonemia with excellent outcome on proactive management","year":2022,"lang":"en","type":"article","venue":"","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Hyperammonemia; Carbonic anhydrase; Medicine; Internal medicine; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001060136,0.0006434491,0.0003967881,0.0003857948,0.0005612735,0.0003706759,0.0003115141,0.001144259,0.0008370413],"category_scores_gemma":[0.0003957687,0.0001453063,0.0003170786,0.0003081897,0.0002906717,0.0003956321,0.0004977474,0.001098341,0.0003373118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004629735,"about_ca_system_score_gemma":0.000502517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00156318,"about_ca_topic_score_gemma":0.001814558,"domain_scores_codex":[0.9998915,0.00001260826,0.00001573048,0.00002929569,0.00001557871,0.00003519371],"domain_scores_gemma":[0.999866,0.00001713444,0.0000261205,0.000007964645,0.000008561474,0.00007421993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001053331,0.0000814263,0.03990811,0.00006276729,0.00002159132,0.9436193,0.0001126711,0.0001471949,0.003559763,0.0003025352,0.001831326,0.01024804],"study_design_scores_gemma":[0.00001323377,0.0001555475,0.04099443,0.00006999441,0.00001754293,0.9548262,0.0001943451,0.0005384685,0.0007757404,0.0004327933,0.001966989,0.00001471364],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692541,0.009721946,0.003860974,0.005163127,0.0005055202,0.0001003849,0.0003642321,0.0002302264,0.01079959],"genre_scores_gemma":[0.991847,0.00305804,0.001415083,0.001303127,0.0003416952,0.00003107963,0.0003665722,0.00003597799,0.00160137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00156318,"threshold_uncertainty_score":0.003359139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612318738034083,"score_gpt":0.254152965568311,"score_spread":0.2380297781879701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}