{"id":"W4292182981","doi":"10.3390/vaccines10081310","title":"Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines","year":2022,"lang":"en","type":"article","venue":"Vaccines","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal; McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Downstream processing; Downstream (manufacturing); Chromatography; Virology; Membrane; Cell culture; Chemistry; Biology; Business; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004345484,0.0004076306,0.0006284093,0.0005035365,0.001067757,0.00006889842,0.000309983,0.0000851509,0.0002744064],"category_scores_gemma":[0.0003812854,0.0003166365,0.0002934154,0.001256146,0.00003937744,0.0001760121,0.0001972759,0.0003974906,0.00001449012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001155062,"about_ca_system_score_gemma":0.000391573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004979474,"about_ca_topic_score_gemma":0.0000119869,"domain_scores_codex":[0.9973313,0.00007774809,0.000507396,0.0006894563,0.0006699443,0.0007241087],"domain_scores_gemma":[0.9982814,0.0001112352,0.0002071536,0.0005585296,0.0006584547,0.0001832356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01372617,0.004803138,0.1764577,0.01353818,0.0008953804,0.0001568252,0.004828219,0.002099593,0.6343769,0.0001108244,0.1294042,0.01960292],"study_design_scores_gemma":[0.02180894,0.003889015,0.01927358,0.0002997424,0.0005923666,0.00009230131,0.002299233,0.002321078,0.4308597,0.0001192317,0.5173118,0.001133035],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838383,0.007361026,0.00005766127,0.002643405,0.0002697085,0.003556837,0.0001498323,0.0005692288,0.001553975],"genre_scores_gemma":[0.9886936,0.00007018176,0.003057953,0.003182409,0.0006767759,0.002732359,0.0001479762,0.0001203806,0.001318372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3879076,"threshold_uncertainty_score":0.9999286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04753732143337648,"score_gpt":0.3467007217280531,"score_spread":0.2991634002946766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}