{"id":"W4292183986","doi":"10.1261/rna.079195.122","title":"circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner","year":2022,"lang":"en","type":"article","venue":"RNA","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novo Nordisk; Novo Nordisk Fonden; Deutsche Forschungsgemeinschaft; Stem Cell Network","keywords":"Biology; Cell biology; Gene expression; Gene; RNA splicing; Paracrine signalling; Alternative splicing; Cell cycle; RNA; Regulation of gene expression; RNA interference; Cell; Gene knockdown; Genetics; Messenger RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001206215,0.0002002797,0.0001700049,0.0002088243,0.0001481039,0.0003641097,0.00009310873,0.0001526919,0.001173632],"category_scores_gemma":[0.0001176586,0.00008841068,0.0001548611,0.0001342741,0.000241147,0.0001305367,0.0001381878,0.0003949305,0.0002640019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001937297,"about_ca_system_score_gemma":0.000209297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003789066,"about_ca_topic_score_gemma":0.0006744624,"domain_scores_codex":[0.9999132,0.00001536168,0.000004247614,0.00002431216,0.00001835577,0.00002447727],"domain_scores_gemma":[0.999925,0.00001644388,0.00001395196,0.0000111002,0.00001214415,0.00002132763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006887098,0.000009135568,0.0002334468,0.0000158871,0.000002483877,0.00002702341,0.000005958374,0.00002085455,0.9981414,0.00004607277,0.00002812944,0.001400694],"study_design_scores_gemma":[0.00002473545,0.0003318848,0.01210006,0.000006384366,0.00002981518,0.0003003697,0.00005335531,0.001219005,0.9819331,0.0001161439,0.003879827,0.000005380653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892157,0.002922214,0.004203552,0.0001587283,0.00005874886,0.00002645477,0.0003901763,0.0002004961,0.002823989],"genre_scores_gemma":[0.9950454,0.001061337,0.002034907,0.00007344571,0.00002419335,0.00001898494,0.0002598164,0.00002806375,0.001453921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173632,"threshold_uncertainty_score":0.003926218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005713754148847797,"score_gpt":0.2173348936966643,"score_spread":0.2116211395478165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}