{"id":"W4292185501","doi":"10.1158/2767-9764.crc-21-0135","title":"Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer","year":2022,"lang":"en","type":"article","venue":"Cancer Research Communications","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation; National Institute of Dental and Craniofacial Research; Free To Breathe; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; North Carolina Biotechnology Center; Lung Cancer Research Foundation; National Cancer Institute; National Institutes of Health; Yale University","keywords":"Immunohistochemistry; Tissue microarray; Head and neck squamous-cell carcinoma; Immunostaining; Medicine; Cancer; Head and neck cancer; Cancer research; Pathology; Oncology; Immune system; HPV infection; Biomarker; Biology; Internal medicine; Cervical cancer; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008185585,0.0002185536,0.000280405,0.0007116357,0.0001762717,0.0004560387,0.0002495162,0.0003154429,0.0003912335],"category_scores_gemma":[0.0009997269,0.0001356013,0.0002248765,0.0005582907,0.0002856081,0.0002571503,0.0004319307,0.000312954,0.0001235488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003531848,"about_ca_system_score_gemma":0.0001889729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001198092,"about_ca_topic_score_gemma":0.002122549,"domain_scores_codex":[0.9997242,0.00008777718,0.00001987281,0.00005945002,0.0000670742,0.00004153206],"domain_scores_gemma":[0.9995838,0.0001019649,0.0001386157,0.00003574146,0.00008331118,0.00005663326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006783445,0.00003308284,0.9693944,0.00004106321,0.0000970781,0.00009342464,0.00003947885,0.0003695887,0.01867243,0.00003087162,0.0001579281,0.01039227],"study_design_scores_gemma":[0.000009941196,0.0002074344,0.9877018,0.000009292904,0.0001067436,0.0004915015,0.000113769,0.004021761,0.006767535,0.0001290996,0.000432351,0.000008754353],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979286,0.001257825,0.000393326,0.00003974902,0.000004828638,0.000007768846,0.0001114285,0.00001284485,0.0002435675],"genre_scores_gemma":[0.9991748,0.000211589,0.0003689979,0.00001293718,0.000004760966,0.000005446286,0.0001348089,0.00000175441,0.00008490987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198092,"threshold_uncertainty_score":0.004329026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1315702452634776,"score_gpt":0.4713348231637256,"score_spread":0.3397645779002479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}