{"id":"W4292185501","doi":"10.1158/2767-9764.crc-21-0135","title":"Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer","year":2022,"lang":"en","type":"article","venue":"Cancer Research Communications","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation; National Institute of Dental and Craniofacial Research; Free To Breathe; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; North Carolina Biotechnology Center; Lung Cancer Research Foundation; National Cancer Institute; National Institutes of Health; Yale University","keywords":"Immunohistochemistry; Tissue microarray; Head and neck squamous-cell carcinoma; Immunostaining; Medicine; Cancer; Head and neck cancer; Cancer research; Pathology; Oncology; Immune system; HPV infection; Biomarker; Biology; Internal medicine; Cervical cancer; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001175891,0.0001755617,0.0003349413,0.0005574916,0.001093761,0.00006084959,0.0005970639,0.00004001476,0.0004641327],"category_scores_gemma":[0.002245239,0.0001646919,0.00003739423,0.001190451,0.0009296665,0.0001306649,0.003563232,0.001384425,0.00001024496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009884516,"about_ca_system_score_gemma":0.001111047,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007841412,"about_ca_topic_score_gemma":0.002911479,"domain_scores_codex":[0.9967718,0.0008907705,0.0003088603,0.0004946439,0.0008614344,0.0006724972],"domain_scores_gemma":[0.9950103,0.003032594,0.00006482762,0.001271971,0.0003042211,0.0003161489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001058416,0.001449112,0.9028795,0.001220627,0.0001702489,0.0002766438,0.005631291,0.00003630215,0.03288332,0.0006592596,0.01842058,0.0353147],"study_design_scores_gemma":[0.004281935,0.0009091194,0.8907805,0.001936674,0.00006919602,0.00008419301,0.003899135,0.001124696,0.001143749,0.0006376798,0.09476171,0.0003714275],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8600319,0.1180257,0.000001506414,0.01744138,0.00004623962,0.002082133,0.00009385544,0.00004499772,0.00223223],"genre_scores_gemma":[0.9431035,0.04359208,0.0002160068,0.0002484665,0.00002920578,0.01193864,0.00002113125,0.00004059045,0.0008104103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08307154,"threshold_uncertainty_score":0.9987655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1315702452634776,"score_gpt":0.4713348231637256,"score_spread":0.3397645779002479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}