{"id":"W4292264022","doi":"10.18609/cgti.2022.111","title":"Manufacturing considerations underpinning viral and non-viral platform selection","year":2022,"lang":"en","type":"article","venue":"Cell and Gene Therapy Insights","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Engineering management; Product (mathematics); Engineering; New product development; Management","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0287354,0.0007029899,0.000801574,0.001492228,0.001897764,0.005642163,0.001516491,0.002496694,0.002908442],"category_scores_gemma":[0.02581058,0.0007967695,0.000896956,0.0005723646,0.002538952,0.003144466,0.003335035,0.00266452,0.001598262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001838125,"about_ca_system_score_gemma":0.002763762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009367031,"about_ca_topic_score_gemma":0.001712555,"domain_scores_codex":[0.9854743,0.003846279,0.001283695,0.001079314,0.007255687,0.001060667],"domain_scores_gemma":[0.9829632,0.01078741,0.001690376,0.0008577526,0.003290006,0.0004112243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0009775665,0.000388769,0.01022806,0.004386525,0.0001763836,0.005416925,0.002808069,0.02102253,0.4487125,0.1141707,0.0113483,0.3803636],"study_design_scores_gemma":[0.0001497978,0.003042615,0.01176425,0.00210426,0.0002730301,0.006931379,0.003420495,0.02140603,0.4711745,0.07085797,0.4085328,0.0003429229],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.2863194,0.08003821,0.4444402,0.02963008,0.004281378,0.003901681,0.000506086,0.0009158604,0.1499671],"genre_scores_gemma":[0.7038118,0.03316843,0.2369799,0.00629696,0.001068908,0.0015486,0.0004269247,0.0004486374,0.01624974],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0287354,"threshold_uncertainty_score":0.1519691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097146895141813,"score_gpt":0.2274589516590393,"score_spread":0.2164874827076211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}