{"id":"W4292291845","doi":"10.3390/cells11162537","title":"Roads to Stat3 Paved with Cadherins","year":2022,"lang":"en","type":"review","venue":"Cells","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Cell biology; STAT3; Cadherin; Biology; Autocrine signalling; STAT protein; Glycoprotein 130; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Cancer research; Chemistry; Receptor; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008759284,0.0002710828,0.001010219,0.0001691774,0.00007502971,0.00002250088,0.0001205355,0.00007579277,0.009611757],"category_scores_gemma":[0.0000181831,0.0001903669,0.0002931695,0.0003379961,0.00001618724,0.00001914907,0.00006962765,0.0005147212,0.000649353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002110884,"about_ca_system_score_gemma":0.0004081324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006824375,"about_ca_topic_score_gemma":0.00001060423,"domain_scores_codex":[0.9988367,0.00004555624,0.0003144313,0.0003434352,0.0002309191,0.0002289582],"domain_scores_gemma":[0.9990992,0.00008394966,0.0001230481,0.0004552568,0.00003374682,0.0002048034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003423805,0.0001951946,0.00000115684,0.006879766,0.0003339849,0.0003428932,0.0001890335,0.000008518837,0.0002899696,0.00004861185,0.0303608,0.9613158],"study_design_scores_gemma":[0.0001609781,0.000594683,7.937584e-7,0.003609713,0.0006726012,0.0001516109,0.00003696138,0.000001140987,0.000134057,4.800253e-7,0.9944243,0.0002126515],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001546414,0.9714531,0.00007265056,0.00003335549,0.0005870415,0.0009904102,0.0001435638,0.00008039844,0.02662397],"genre_scores_gemma":[0.000004373411,0.9690994,0.0003555309,0.0002469344,0.0002931405,0.0001966796,0.0002294819,0.00008644179,0.029488],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9640635,"threshold_uncertainty_score":0.9912936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1102745235419243,"score_gpt":0.3679403702720192,"score_spread":0.257665846730095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}