{"id":"W4292291845","doi":"10.3390/cells11162537","title":"Roads to Stat3 Paved with Cadherins","year":2022,"lang":"en","type":"review","venue":"Cells","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Cell biology; STAT3; Cadherin; Biology; Autocrine signalling; STAT protein; Glycoprotein 130; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Cancer research; Chemistry; Receptor; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007264462,0.0002577797,0.0001932406,0.0003635154,0.0003933753,0.001044398,0.0002189776,0.0004005788,0.01393968],"category_scores_gemma":[0.0001218633,0.0002302747,0.0004774386,0.0002230265,0.000307908,0.0004760056,0.0006146726,0.00126528,0.005000742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000810214,"about_ca_system_score_gemma":0.0003212104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008225458,"about_ca_topic_score_gemma":0.001265968,"domain_scores_codex":[0.999739,0.0000137736,0.000009496725,0.00005243447,0.00008603112,0.0000992077],"domain_scores_gemma":[0.9998522,0.00001056902,0.00003308091,0.00001968814,0.00002416469,0.0000602194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002453462,0.00004018102,0.001293142,0.0001077985,0.00001638487,0.0002343902,0.00005297763,0.0001678767,0.978789,0.004278859,0.002477649,0.0122965],"study_design_scores_gemma":[0.00006565858,0.0004063849,0.04364388,0.00006161245,0.00005027492,0.001338237,0.0002831994,0.003379782,0.79899,0.002958372,0.1487931,0.00002955583],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9082071,0.01651262,0.007133008,0.003127923,0.0007013673,0.0000646304,0.002827357,0.001527532,0.05989845],"genre_scores_gemma":[0.9527095,0.002655839,0.001344144,0.0007817101,0.00008608842,0.00002720249,0.002109507,0.0001075832,0.04017848],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01393968,"threshold_uncertainty_score":0.04663289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1102745235419243,"score_gpt":0.3679403702720192,"score_spread":0.257665846730095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}