{"id":"W4292302487","doi":"10.7759/cureus.28162","title":"Cardiotoxicity Associated With Chimeric Antigen Receptor (CAR)-T Cell Therapy for Hematologic Malignancies: A Systematic Review","year":2022,"lang":"en","type":"review","venue":"Cureus","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Systematic review; Cochrane Library; Chimeric antigen receptor; Cardiotoxicity; Randomized controlled trial; MEDLINE; Clinical trial; Adverse effect; Intensive care medicine; Narrative review; Internal medicine; Cancer; Immunotherapy; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002336344,0.0009642884,0.008827708,0.0002003508,0.0002490829,0.00005238333,0.0008215521,0.0004412944,0.0053867],"category_scores_gemma":[0.001044246,0.0006118586,0.002135262,0.001351538,0.0001291996,0.00005783181,0.0001415801,0.0009234786,0.00008266071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001289185,"about_ca_system_score_gemma":0.00128266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002770815,"about_ca_topic_score_gemma":0.000003902364,"domain_scores_codex":[0.9941339,0.001325653,0.00142256,0.001019979,0.00119932,0.0008985557],"domain_scores_gemma":[0.9951465,0.001277677,0.001263406,0.001741548,0.000288883,0.0002820573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006010269,0.0003822725,0.000005271492,0.9799378,0.002994687,0.0000804623,0.00008418442,6.621379e-8,0.00008298312,0.000005141251,0.006998402,0.009368622],"study_design_scores_gemma":[0.0007686322,0.001017446,4.443022e-7,0.3359547,0.003240557,0.0002255743,0.00005284312,0.000001289869,0.00003074802,0.00000242206,0.6582041,0.0005012153],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002840131,0.9714202,0.0000197475,0.0000402776,0.0002501234,0.02628664,0.0003198175,0.0002082559,0.001426584],"genre_scores_gemma":[0.000003580206,0.9803901,0.0001383224,0.0004192922,0.0001532393,0.0103311,0.001182289,0.0002866844,0.007095363],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6512057,"threshold_uncertainty_score":0.9996333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09833758926295857,"score_gpt":0.364639551080973,"score_spread":0.2663019618180145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}