{"id":"W4292309532","doi":"10.1186/s13613-022-01051-3","title":"A stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score","year":2022,"lang":"en","type":"article","venue":"Annals of Intensive Care","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"Fonds de Recherche du Québec - Santé; Sanofi Pasteur; bioMérieux; Agence Nationale de la Recherche; Fondation Générale de Santé; GlaxoSmithKline foundation; Royal College of Physicians and Surgeons of Canada","keywords":"Medicine; Cohort; Internal medicine; Sepsis; Procalcitonin; Framingham Risk Score; Septic shock; Prospective cohort study; Cohort study; Anesthesiology; Mechanical ventilation; Intensive care medicine; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001654522,0.0001246513,0.0002551245,0.0001412228,0.0001630321,0.00001686953,0.00006539311,0.00004731917,0.0003183156],"category_scores_gemma":[0.001523081,0.00009448567,0.0001228088,0.0003529274,0.00005533325,0.00006440852,0.00005399633,0.0002741,0.000006468092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001086833,"about_ca_system_score_gemma":0.0001704237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002068236,"about_ca_topic_score_gemma":0.0003158677,"domain_scores_codex":[0.9988625,0.0001074542,0.0003380858,0.0002517261,0.0002740162,0.0001662221],"domain_scores_gemma":[0.9943987,0.0001404006,0.00007679544,0.0003112315,0.005001629,0.00007123113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005540731,0.00318974,0.4024804,0.001533849,0.001428202,0.0009616887,0.04872221,0.001394949,0.04509151,0.02941106,0.2731221,0.1871236],"study_design_scores_gemma":[0.0008610141,0.004162013,0.8705593,0.0002332406,0.00009764499,0.00008430838,0.07579523,0.00003271724,0.04663517,0.0004220915,0.0009658921,0.0001514017],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680876,0.0009472949,0.000007923998,0.02839013,0.0003804069,0.0006403149,0.00009639162,0.0000234369,0.001426566],"genre_scores_gemma":[0.9889277,0.00009542792,0.000005312286,0.01020141,0.00007883378,0.0004008386,0.0002491491,0.00001416221,0.00002715145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4680789,"threshold_uncertainty_score":0.3853014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1911002608496996,"score_gpt":0.4070553552159065,"score_spread":0.215955094366207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}