{"id":"W4292399167","doi":"10.1007/s40266-022-00970-x","title":"Opioid Initiation and the Hazard of Falls or Fractures Among Older Adults with Varying Levels of Central Nervous System Depressant Burden","year":2022,"lang":"en","type":"article","venue":"Drugs & Aging","topic":"Opioid Use Disorder Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's College Hospital; Health Sciences Centre; Sunnybrook Hospital; Sunnybrook Health Science Centre; Toronto Rehabilitation Institute; University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Hazard ratio; Medical prescription; Opioid; Cohort; Analgesic; Proportional hazards model; Population; Poison control; Cohort study; Internal medicine; Emergency medicine; Anesthesia; Pharmacology; Confidence interval; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001834601,0.0001538921,0.0003700944,0.0000906166,0.0001419517,0.00001488247,0.00009724321,0.00002711925,0.00004823902],"category_scores_gemma":[0.00002411488,0.0000911912,0.00005788843,0.0001551601,0.00008681037,0.0000777747,0.0001003148,0.0001645659,3.067528e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008220434,"about_ca_system_score_gemma":0.0001038837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001420436,"about_ca_topic_score_gemma":0.00002074197,"domain_scores_codex":[0.998701,0.0001139569,0.0003097301,0.0002280138,0.0004259988,0.0002213222],"domain_scores_gemma":[0.9991874,0.0001636015,0.0002619429,0.0002627959,0.00006863096,0.00005566103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"qualitative","study_design_gemma":"observational","study_design_scores_codex":[0.004733979,0.0004567331,0.3175001,0.004591377,0.001187344,0.0002647676,0.6292889,0.007336229,0.001056461,0.0004120474,0.0001126353,0.03305948],"study_design_scores_gemma":[0.01539355,0.0002768269,0.9053097,0.002429496,0.000726114,0.00009323412,0.05998888,0.007476741,0.008007401,0.00001790153,0.00004672635,0.0002334548],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967,0.001214664,0.0001822948,0.0002384075,0.00007598443,0.0009265735,0.00004029338,0.00003981352,0.0005819697],"genre_scores_gemma":[0.9994025,0.00002917102,0.0002373271,0.00008653047,0.00005055645,0.000098892,0.00003015995,0.00002758679,0.00003728502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5878096,"threshold_uncertainty_score":0.3718669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007183984478521583,"score_gpt":0.2372998120704857,"score_spread":0.2301158275919641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}