{"id":"W4292400817","doi":"10.1002/ppsc.202200121","title":"Reversible and Irreversible HAuCl<sub>4</sub> Binding to DNA for Seeded Gold Nanoparticle Growth and Opposite DNA and Aptamers Colorimetric Sensing Outcomes","year":2022,"lang":"en","type":"article","venue":"Particle & Particle Systems Characterization","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"China Scholarship Council; University of Waterloo; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Aptamer; DNA; Chemistry; Adsorption; Colloidal gold; Biophysics; Biosensor; Nanoparticle; Combinatorial chemistry; Nanotechnology; Biochemistry; Materials science; Biology; Organic chemistry; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004361371,0.0005012051,0.0002440084,0.0002429827,0.0001973039,0.0003595976,0.000772015,0.0006428181,0.0009748167],"category_scores_gemma":[0.0006467526,0.0004293478,0.0002815677,0.0001552263,0.000483184,0.0002942572,0.0003097361,0.0005189506,0.0004903292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006577448,"about_ca_system_score_gemma":0.0002792762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001479989,"about_ca_topic_score_gemma":0.002839397,"domain_scores_codex":[0.9993333,0.0001201789,0.0000397882,0.0001503312,0.0002673607,0.00008900382],"domain_scores_gemma":[0.9995751,0.0001645465,0.00007413532,0.00004258004,0.0001039688,0.00003962173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002124089,0.000005801577,0.00003258348,0.00003302212,0.000001828799,0.00002129295,0.00001874915,0.00005350674,0.9991078,0.00005784189,0.00001659567,0.0006298643],"study_design_scores_gemma":[0.000001949456,0.00002247166,0.0001599324,8.127564e-7,0.000001183519,0.00001616166,0.000004387296,0.0004066211,0.9992282,0.000007361696,0.0001477332,0.000003181933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578632,0.001654824,0.03508554,0.0001459414,0.0001346455,0.0001661944,0.0002964986,0.0004204651,0.004232646],"genre_scores_gemma":[0.962212,0.0005434276,0.03192753,0.00007220144,0.00001388047,0.0001411635,0.0002062449,0.00005721057,0.004826263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001479989,"threshold_uncertainty_score":0.004772365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287084269467049,"score_gpt":0.23971791018239,"score_spread":0.2268470674877195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}