{"id":"W4292452093","doi":"10.3389/fviro.2022.957124","title":"Retinoids: novel potential therapeutics in the pursuit of HIV-1 cure","year":2022,"lang":"en","type":"article","venue":"Frontiers in Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Antiretroviral therapy; Retinoic acid; Human immunodeficiency virus (HIV); Virus latency; Immunology; Immune system; Virology; Medicine; CD8; Viral replication; Virus; Biology; Viral load; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005313997,0.0004285664,0.0006763406,0.000946695,0.0002819623,0.001023921,0.0004159602,0.0008648616,0.003714802],"category_scores_gemma":[0.0002496328,0.0001837865,0.0004914843,0.0003431861,0.0006992762,0.0008911807,0.0005950278,0.002298463,0.001525583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000518475,"about_ca_system_score_gemma":0.000409997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003681465,"about_ca_topic_score_gemma":0.001071688,"domain_scores_codex":[0.9998406,0.00004641963,0.0000084559,0.0000268681,0.00004285203,0.00003470729],"domain_scores_gemma":[0.999886,0.00003208953,0.00002209134,0.000009783786,0.00002299827,0.0000270001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001300095,0.0004775013,0.0007305028,0.004281314,0.0001242911,0.001004424,0.000264698,0.001445746,0.1566067,0.05143993,0.01695803,0.7653667],"study_design_scores_gemma":[0.000433074,0.002394152,0.002240767,0.001529816,0.0001896132,0.003081845,0.0002829564,0.001245344,0.05791853,0.02479447,0.9058005,0.00008886635],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01523331,0.9555868,0.006276723,0.007285412,0.0008771637,0.00007118593,0.0002360782,0.0001563522,0.01427701],"genre_scores_gemma":[0.1119015,0.8628902,0.009820403,0.002666036,0.001223603,0.0001114596,0.0002399476,0.00003187835,0.01111493],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003714802,"threshold_uncertainty_score":0.01242727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279037724165687,"score_gpt":0.2414134317958992,"score_spread":0.2286230545542424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}