{"id":"W4292461694","doi":"10.1038/s41598-022-18204-w","title":"Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute; Alberta Children's Hospital; University of Toronto; Toronto General Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Alberta Innovates; Killam Trusts; University of Calgary; Calgary Firefighters Burn Treatment Society; California HIV/AIDS Research Program","keywords":"Wound healing; Keratinocyte; Human skin; Self-healing hydrogels; Epidermis (zoology); Peptide; Medicine; Wound closure; In vitro; Cancer research; Surgery; Chemistry; Biology; Anatomy; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159247,0.000281153,0.0001752349,0.000144907,0.00006145502,0.0001547525,0.00009793406,0.0001463463,0.001016583],"category_scores_gemma":[0.00007503088,0.00007439466,0.0001813109,0.00008665403,0.000092686,0.0001849712,0.00009718999,0.0003603247,0.0001458521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007923432,"about_ca_system_score_gemma":0.0001124504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003427215,"about_ca_topic_score_gemma":0.0005769033,"domain_scores_codex":[0.9999377,0.00001071199,0.00000718111,0.00001333326,0.00001651051,0.00001460616],"domain_scores_gemma":[0.9999318,0.00002004151,0.0000172715,0.000008579495,0.000006016125,0.00001629509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008122717,0.00008075115,0.00004652223,0.00003564466,0.000002514205,0.00003688594,0.00001392311,0.00008974656,0.9979991,0.00002584718,0.00003782497,0.001549917],"study_design_scores_gemma":[0.00001538295,0.0009053265,0.001017211,0.000005402885,0.000008581192,0.00008763113,0.00001836474,0.0007354257,0.9961695,0.000009937938,0.00102467,0.000002530922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936323,0.001742415,0.002901486,0.0000565604,0.00008940842,0.00004905185,0.0001410638,0.00008807021,0.001299727],"genre_scores_gemma":[0.9936002,0.001376359,0.003085224,0.00004334867,0.0000186074,0.00002650701,0.0001363984,0.0000154586,0.001697913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001016583,"threshold_uncertainty_score":0.003400803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01989789710022323,"score_gpt":0.3104219356448014,"score_spread":0.2905240385445782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}