{"id":"W4292461694","doi":"10.1038/s41598-022-18204-w","title":"Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute; Alberta Children's Hospital; University of Toronto; Toronto General Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Alberta Innovates; Killam Trusts; University of Calgary; Calgary Firefighters Burn Treatment Society; California HIV/AIDS Research Program","keywords":"Wound healing; Keratinocyte; Human skin; Self-healing hydrogels; Epidermis (zoology); Peptide; Medicine; Wound closure; In vitro; Cancer research; Surgery; Chemistry; Biology; Anatomy; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007196601,0.00008522243,0.0002185604,0.0002505234,0.0003669091,0.00001968789,0.00006233323,0.00003541112,0.0001000976],"category_scores_gemma":[0.00002742433,0.00007979867,0.00006182853,0.0007116704,0.0001554919,0.00008720196,0.00004429197,0.00007505481,0.000001055224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009595265,"about_ca_system_score_gemma":0.0001355856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000421924,"about_ca_topic_score_gemma":0.00003580345,"domain_scores_codex":[0.9983856,0.00004243707,0.0005151007,0.000401846,0.0005295817,0.0001254112],"domain_scores_gemma":[0.9985394,0.000008802731,0.0005123569,0.0006256609,0.0002457145,0.00006806233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002468935,0.003473738,0.3340601,0.0003136321,0.0002578832,0.0001789989,0.008785453,0.001282078,0.6325465,0.001536663,0.0007378955,0.01658008],"study_design_scores_gemma":[0.002131667,0.001412981,0.1053756,0.0001020357,0.000374139,0.0005976668,0.002755867,0.002856471,0.8359554,0.03965094,0.008446035,0.0003412802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978718,0.00004383643,0.0001016287,0.00002629824,0.0005642469,0.0004526127,0.00001059108,0.00003784111,0.0008911805],"genre_scores_gemma":[0.9980076,7.443309e-7,0.0004506482,0.000009726857,0.00002690685,0.00006987561,0.0008290097,0.00001306383,0.0005924436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2286846,"threshold_uncertainty_score":0.3254096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01989789710022323,"score_gpt":0.3104219356448014,"score_spread":0.2905240385445782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}