{"id":"W4292615550","doi":"10.1016/j.cll.2022.05.003","title":"Copy Number Analysis in Cancer Diagnostic Testing","year":2022,"lang":"en","type":"review","venue":"Clinics in Laboratory Medicine","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Fluorescence in situ hybridization; Computational biology; Fish <Actinopterygii>; Medicine; Biology; Bioinformatics; Oncology; Chromosome; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001707658,0.001146262,0.001915054,0.003777626,0.0002448052,0.001248224,0.001541125,0.00173718,0.003271964],"category_scores_gemma":[0.003747583,0.0004168305,0.0006497373,0.003174392,0.0010185,0.001337018,0.000958606,0.002624807,0.001496798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009537925,"about_ca_system_score_gemma":0.001456146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002144012,"about_ca_topic_score_gemma":0.003456241,"domain_scores_codex":[0.9993464,0.0001716102,0.00007994297,0.0001269103,0.0002313553,0.00004377323],"domain_scores_gemma":[0.9982656,0.001165322,0.0001289761,0.00004070763,0.0003076194,0.00009185495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007007481,0.00003401119,0.0004277637,0.006353946,0.00009756296,0.0003998151,0.00003137345,0.0004518947,0.0006339985,0.002646101,0.04260379,0.9462497],"study_design_scores_gemma":[0.0000635349,0.0001004493,0.002133122,0.007344329,0.0004392529,0.005140941,0.00008811017,0.0004083708,0.0005738758,0.006166879,0.9774848,0.0000563489],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004496923,0.9984249,0.0002635229,0.0003713196,0.0003084764,0.000003628765,0.00001760681,0.00000722144,0.0005584651],"genre_scores_gemma":[0.0008313592,0.9965605,0.000503724,0.0006058303,0.0008718188,0.000008701339,0.0000517164,0.000003135276,0.0005631673],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003777626,"threshold_uncertainty_score":0.0109458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06783115621798493,"score_gpt":0.3948550410333133,"score_spread":0.3270238848153284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}