{"id":"W4292636384","doi":"10.1371/journal.pone.0273116","title":"A genome-wide association study of total child psychiatric problems scores","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Child and Adolescent Psychosocial and Emotional Development","field":"Psychology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Mental Health; National Institute on Aging; Academy of Finland; National Institute on Alcohol Abuse and Alcoholism; Horizon 2020; Signe ja Ane Gyllenbergin Säätiö; Medical Research Council; National Institute on Drug Abuse; Paavo Nurmen Säätiö; Diabetesliitto; Kela; Tampereen Tuberkuloosisäätiö; Sydäntutkimussäätiö; National Heart, Lung, and Blood Institute; Emil Aaltosen Säätiö; Juho Vainion Säätiö; Foundation for Cardiovascular Research; Lundbeckfonden; Suomen Kulttuurirahasto; ZonMw; Economic and Social Research Council; European Commission; Steno Diabetes Center Copenhagen; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Genome-wide association study; Association (psychology); Psychiatric genetics; Psychiatry; Medicine; Biology; Psychology; Genetics; Schizophrenia (object-oriented programming); Single-nucleotide polymorphism; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009044489,0.0004205134,0.0004360579,0.0009068357,0.0005450075,0.0005868507,0.0003364168,0.0004980619,0.003046569],"category_scores_gemma":[0.002112492,0.0003034515,0.0005757021,0.001694477,0.000357275,0.0002287116,0.000587853,0.0006850329,0.0002443728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002926421,"about_ca_system_score_gemma":0.000433549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009676511,"about_ca_topic_score_gemma":0.01220058,"domain_scores_codex":[0.9991269,0.0002916958,0.00005148019,0.0003147325,0.0001242608,0.00009101803],"domain_scores_gemma":[0.9989586,0.0003230957,0.0003020687,0.0001345315,0.00008844779,0.0001931341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002727484,0.00004821642,0.9934582,0.00002646316,0.000678285,0.0003028875,0.0001251886,0.00006572202,0.001858298,0.00008558665,0.0003132577,0.002765135],"study_design_scores_gemma":[0.00001715415,0.00004801129,0.9991156,0.000004383327,0.0001078704,0.0002832338,0.00003805151,0.00006777001,0.00006405514,0.000033353,0.0002184924,0.000002074706],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970393,0.0003920207,0.000362881,0.0001102076,0.000009428471,0.00001695363,0.00108761,0.00001846327,0.0009631951],"genre_scores_gemma":[0.997669,0.0002114362,0.0005859371,0.00004166008,0.000008241419,0.00002250898,0.0009802447,0.000008658011,0.0004723293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009676511,"threshold_uncertainty_score":0.01924038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02718630262636636,"score_gpt":0.2346833061104929,"score_spread":0.2074970034841266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}