{"id":"W4292702411","doi":"10.1002/anie.202209143","title":"Photoredox Activation of Anhydrides for the Solvent‐Controlled Switchable Synthesis of <i>gem</i> ‐Difluoro Compounds**","year":2022,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"SNC-Lavalin (Canada)","funders":"Compute Canada; Université de Fribourg; Alliance de recherche numérique du Canada; Eidgenössische Technische Hochschule Zürich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Solvent; Chemistry; Combinatorial chemistry; Photoredox catalysis; Organic chemistry; Photochemistry; Catalysis; Photocatalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001624437,0.0003969674,0.000102637,0.0001137517,0.00009036946,0.0001492898,0.0002373412,0.0002643573,0.001480054],"category_scores_gemma":[0.0001310943,0.00009618585,0.0001516421,0.00009998045,0.0001426386,0.0003044974,0.0001785619,0.0003232278,0.0003860958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003059332,"about_ca_system_score_gemma":0.0001523372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004646004,"about_ca_topic_score_gemma":0.001090659,"domain_scores_codex":[0.9999176,0.0000106531,0.000005427606,0.00002373101,0.00001463602,0.00002785415],"domain_scores_gemma":[0.9999477,0.00001040764,0.00002310746,0.000006008932,0.000005652083,0.000007127201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003176943,0.00001116471,0.00007592116,0.00007264394,0.000003069809,0.0000705085,0.00001938146,0.00008057417,0.9946349,0.0008663729,0.0001981528,0.003935569],"study_design_scores_gemma":[0.000004654438,0.00007399407,0.0002684655,0.000002730271,0.00000249938,0.000101989,0.000005764525,0.0003254939,0.9944363,0.00004148547,0.004732822,0.000003881466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9424643,0.004335548,0.03067676,0.0003642497,0.0001669811,0.0001418378,0.0004336654,0.0005067065,0.02091005],"genre_scores_gemma":[0.9896596,0.001226494,0.006117745,0.00008408507,0.00002126908,0.00003048114,0.0001262293,0.00003129648,0.002702812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001480054,"threshold_uncertainty_score":0.004951239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05154327105907862,"score_gpt":0.3586947124266089,"score_spread":0.3071514413675303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}