{"id":"W4292702985","doi":"10.1111/php.13699","title":"Capturing <scp>Protein–Nucleic</scp> Acid Interactions by <scp>High‐Intensity Laser‐Induced</scp> Covalent Cross‐Linking<sup>†</sup>","year":2022,"lang":"en","type":"review","venue":"Photochemistry and Photobiology","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Agence Nationale de la Recherche","keywords":"Nucleic acid; Histone; Chromatin; Chromatin immunoprecipitation; DNA; Chemistry; Biomolecule; DNA replication; DNA-binding protein; Computational biology; Transcription (linguistics); Biochemistry; Cell biology; Biology; Gene; Transcription factor; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005778669,0.001404893,0.002112349,0.0001421102,0.0007408357,0.0001681209,0.00120567,0.001511654,0.0002430153],"category_scores_gemma":[0.0009011133,0.001375676,0.0008448766,0.0003028621,0.0003821095,0.00002162011,0.001395768,0.001827717,0.00004123761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611073,"about_ca_system_score_gemma":0.0004921846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001483564,"about_ca_topic_score_gemma":0.000009068103,"domain_scores_codex":[0.9946982,0.0002658274,0.001167362,0.00224895,0.000303826,0.001315803],"domain_scores_gemma":[0.9966568,0.0003388126,0.0009441708,0.001325315,0.0001980557,0.0005368747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003978201,0.0003677191,0.000007849098,0.006128149,0.000898028,0.00007664885,0.0001842088,0.000005676381,0.9775649,0.00001634984,0.002681368,0.01202929],"study_design_scores_gemma":[0.0003582877,0.0002122145,2.126481e-7,0.0006077398,0.0002734458,0.0007157641,0.0001689575,0.00001158569,0.4729468,0.00009704059,0.5243849,0.0002230551],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4624799,0.528896,0.00008477402,0.00001190233,0.0007355288,0.002083465,0.003617198,0.0001480549,0.001943167],"genre_scores_gemma":[0.06885669,0.9130127,0.0001345286,0.0004540341,0.000796292,0.002258042,0.009584295,0.0002577345,0.00464564],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5217035,"threshold_uncertainty_score":0.9998701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02378350327898202,"score_gpt":0.2830154815251333,"score_spread":0.2592319782461513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}