{"id":"W4292757077","doi":"10.1099/jgv.0.001771","title":"Thermal stabilization of enterovirus A 71 and production of antigenically stabilized empty capsids","year":2022,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; International Seafood Sustainability Foundation; Saudi Arabia Cultural Bureau in London; Wellcome Trust; World Health Organization","keywords":"Capsid; Virology; Biology; Poliovirus; Enterovirus; Virus; Enterovirus 71; Population; Antigen; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001764456,0.0001937755,0.0001661777,0.0001407681,0.0001270591,0.0002616108,0.0001617605,0.0001356859,0.0005603699],"category_scores_gemma":[0.0003076577,0.0001056053,0.0002025216,0.0001041774,0.000208506,0.0001416061,0.0002029986,0.0002731877,0.0001141381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001415091,"about_ca_system_score_gemma":0.00008503293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003773443,"about_ca_topic_score_gemma":0.0004932,"domain_scores_codex":[0.9998599,0.00003675091,0.00001530258,0.0000250693,0.00003298405,0.00002995243],"domain_scores_gemma":[0.9998691,0.00003567986,0.00003383543,0.00002828356,0.00001784532,0.00001520601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004598319,0.00001563446,0.0001827203,0.000009631847,0.000002595102,0.00002210645,0.00001301047,0.0002313017,0.9989007,0.00005810919,0.00001070281,0.0005075008],"study_design_scores_gemma":[0.000005411628,0.0005475113,0.003355678,0.000004247162,0.00001038174,0.0002048521,0.00002951071,0.00150983,0.993612,0.00003862847,0.0006761365,0.000005690706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977181,0.0001456055,0.001745041,0.00001094901,0.00000705858,0.00001770576,0.00004981751,0.00001476853,0.000291057],"genre_scores_gemma":[0.9963571,0.0001551738,0.002403477,0.00001347243,0.000004165975,0.00001715417,0.0001873247,0.00002083524,0.0008411999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005603699,"threshold_uncertainty_score":0.001874626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02033256284846693,"score_gpt":0.3053837785462555,"score_spread":0.2850512156977886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}