{"id":"W4292879115","doi":"10.3390/jof8090896","title":"Whole Genome Sequencing Shows Genetic Diversity, as Well as Clonal Complex and Gene Polymorphisms Associated with Fluconazole Non-Susceptible Isolates of Candida tropicalis","year":2022,"lang":"en","type":"article","venue":"Journal of Fungi","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council; Medical Research Council; National University Health System; NSW Health Pathology; Royal College of Pathologists of Australasia","keywords":"Biology; Fluconazole; Candida tropicalis; Multilocus sequence typing; Genetics; Single-nucleotide polymorphism; Genetic diversity; Genetic variation; Whole genome sequencing; Genome; Gene; Genotype; Microbiology; Population; Antifungal","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000168413,0.0001936627,0.0001815088,0.0008025667,0.0002396332,0.0003458071,0.0001162865,0.0002008193,0.0009170557],"category_scores_gemma":[0.0005840303,0.0000966979,0.0002029485,0.001166219,0.0001809951,0.0001004119,0.0001717971,0.0002210158,0.0001316327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003057853,"about_ca_system_score_gemma":0.0002688366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01633968,"about_ca_topic_score_gemma":0.02985344,"domain_scores_codex":[0.9998047,0.00001536356,0.00001469231,0.0000634526,0.00006493368,0.00003694827],"domain_scores_gemma":[0.9996282,0.00008572807,0.0001261119,0.00003257739,0.00007286527,0.00005458632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003239052,0.00005313828,0.3835316,0.0001322641,0.0001934419,0.000520827,0.0007675172,0.0007873464,0.5839779,0.0001425665,0.0004315522,0.02913791],"study_design_scores_gemma":[0.000004104607,0.00004652223,0.992784,0.000006503249,0.00003340367,0.000601267,0.0001412073,0.0003115226,0.005301304,0.00002886877,0.0007369259,0.000004275922],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984894,0.0002044982,0.0002783019,0.00001823674,0.00000104179,0.000004133199,0.0006872257,0.000006958798,0.0003101832],"genre_scores_gemma":[0.9974086,0.0001665777,0.0005798229,0.00003055653,0.000002828604,0.000005013904,0.001527497,0.000004819388,0.0002743055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01633968,"threshold_uncertainty_score":0.03248918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01886746366459565,"score_gpt":0.23956637102579,"score_spread":0.2206989073611943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}