{"id":"W4292937027","doi":"10.1097/corr.0000000000002335","title":"Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN","year":2022,"lang":"en","type":"article","venue":"Clinical Orthopaedics and Related Research","topic":"Musculoskeletal synovial abnormalities and treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"Medicine; Placebo; Pigmented villonodular synovitis; Randomized controlled trial; Population; Surgery; Placebo-controlled study; Pain relief; Physical therapy; Double blind; Internal medicine; Synovitis; Arthritis; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001368784,0.0004992613,0.0009043171,0.0001581595,0.0001879056,0.0005304908,0.000362363,0.0004050373,0.002642913],"category_scores_gemma":[0.001041807,0.0001385524,0.001270993,0.0001719756,0.000353653,0.0004500864,0.0001984469,0.001206518,0.0003601881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005067925,"about_ca_system_score_gemma":0.0005474052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005343362,"about_ca_topic_score_gemma":0.002212733,"domain_scores_codex":[0.9996947,0.0001319686,0.00003087687,0.00004364623,0.00003713882,0.00006161172],"domain_scores_gemma":[0.9994015,0.0001763504,0.0001656072,0.00003794703,0.00006781578,0.0001508438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.575188,0.02649943,0.01406238,0.005208756,0.003016645,0.0003980687,0.0005072899,0.002058674,0.03866982,0.0006043796,0.009275872,0.3245108],"study_design_scores_gemma":[0.4673294,0.4519469,0.05282061,0.0006662977,0.003100546,0.001142678,0.0003729303,0.001195634,0.006628683,0.0005858178,0.01413588,0.00007460541],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754407,0.01809607,0.0004840506,0.0007700466,0.0001650504,0.0008467968,0.001214393,0.00005190822,0.002931046],"genre_scores_gemma":[0.9884933,0.006392678,0.0005737864,0.001183983,0.0001691644,0.0004364047,0.00158293,0.0000125786,0.001155204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002642913,"threshold_uncertainty_score":0.008841395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0323996117791638,"score_gpt":0.3267602317450881,"score_spread":0.2943606199659243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}