{"id":"W4293001316","doi":"10.54097/hset.v8i.1196","title":"Unleashing Anti-Tumor Activity of Natural Killer Cells Via Modulation of Immune Checkpoints Receptors and Molecules","year":2022,"lang":"en","type":"article","venue":"Highlights in Science Engineering and Technology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cell biology; Receptor; Intracellular; Signal transduction; Innate immune system; Biology; Immune system; Cancer immunotherapy; Immune checkpoint; Immunotherapy; Cancer research; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219038,0.0001816762,0.0001597641,0.0001690111,0.00005234065,0.0002543181,0.0001282958,0.0001474475,0.0007859224],"category_scores_gemma":[0.0000827343,0.00004245533,0.0001283909,0.00007571557,0.0001598628,0.0002339638,0.0001694256,0.0002909259,0.0001342028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001458471,"about_ca_system_score_gemma":0.0001673073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001059894,"about_ca_topic_score_gemma":0.0001532121,"domain_scores_codex":[0.9999411,0.00001255652,0.000004542395,0.000007540766,0.00001673886,0.00001757875],"domain_scores_gemma":[0.9999794,0.000004660215,0.000005923564,0.000001905935,0.000003976366,0.00000413118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001731289,0.00005520109,0.0003647562,0.0004319146,0.00001102201,0.0001685368,0.00003106157,0.0002888071,0.9409431,0.002637537,0.0002405086,0.05465458],"study_design_scores_gemma":[0.00004879126,0.001030289,0.003775487,0.0000813361,0.00004613776,0.0009414911,0.00009316031,0.001372629,0.9504106,0.001833213,0.0403579,0.000008907319],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8011156,0.1692207,0.01584874,0.00120872,0.0002665619,0.00006557528,0.00009629296,0.0001346019,0.01204322],"genre_scores_gemma":[0.9505457,0.04256444,0.00272272,0.0002400542,0.0001313522,0.00002960974,0.00005091996,0.000008764108,0.003706533],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0007859224,"threshold_uncertainty_score":0.002629161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003734019203040667,"score_gpt":0.1913305111117747,"score_spread":0.187596491908734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}