{"id":"W4293005021","doi":"10.1038/s41590-022-01291-2","title":"Eosinophil–lymphocyte interactions in the tumor microenvironment and cancer immunotherapy","year":2022,"lang":"en","type":"review","venue":"Nature Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Varda and Boaz Dotan Research Center for Hemato-Oncology Research, Tel Aviv University; United States-Israel Binational Science Foundation; Azrieli Foundation; Israel Cancer Research Fund; Israel Science Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Campaign Urging Research for Eosinophilic Disease; Israel Cancer Association","keywords":"Tumor microenvironment; Eosinophil; Immunotherapy; Cancer immunotherapy; Immunology; Cancer; Lymphocyte; Cancer research; Tumor-infiltrating lymphocytes; Medicine; Biology; Immune system; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003550185,0.0005789017,0.001198666,0.0005301163,0.000369096,0.00004129116,0.0006425144,0.0006880859,0.005988676],"category_scores_gemma":[0.00005145936,0.0004122345,0.0003914153,0.0003688591,0.0003002888,0.0001222919,0.0002401995,0.005282786,0.000261671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007664465,"about_ca_system_score_gemma":0.0001869321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003464923,"about_ca_topic_score_gemma":0.00006184721,"domain_scores_codex":[0.996631,0.001399699,0.0007624974,0.0006408627,0.00006294682,0.0005030172],"domain_scores_gemma":[0.9981916,0.0006390666,0.0005312314,0.0006093102,0.00001863024,0.00001015482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002105053,0.0002821996,0.000007488864,0.00033259,0.0008895246,0.00002892801,0.0004001588,5.507448e-7,0.001536012,0.0001619262,0.006923286,0.9892268],"study_design_scores_gemma":[0.0008424595,0.000146879,0.00009951123,0.0006075738,0.0002424958,0.002154318,0.0003615654,3.040645e-7,0.00007087153,0.00001218806,0.9950987,0.0003631943],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001995567,0.9869272,0.000001795626,0.0003388531,0.01100027,0.0008634034,0.00002675986,0.00007665443,0.0005655055],"genre_scores_gemma":[0.0002386104,0.9924572,0.000005474699,0.001343959,0.00008411433,0.001001196,0.0004892273,0.00009246713,0.004287744],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9888636,"threshold_uncertainty_score":0.9998329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0193582472612447,"score_gpt":0.3033116993315441,"score_spread":0.2839534520702994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}