{"id":"W4293030248","doi":"10.3390/ijms23179538","title":"Vitelline Membrane Protein 26 Mutagenesis, Using CRISPR/Cas9, Results in Egg Collapse in Plutella xylostella","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Fujian Agriculture and Forestry University; National Natural Science Foundation of China","keywords":"Vitelline membrane; Biology; Plutella; Mutant; Yolk; Gene; Frameshift mutation; Molecular biology; Genetics; Oocyte; Exon; Embryo; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001133586,0.0001191499,0.0001500244,0.0004000318,0.00005526224,0.00004824367,0.0006733395,0.00004484347,0.00002083368],"category_scores_gemma":[0.0001371975,0.0001203763,0.00009071352,0.0003538344,0.00007480675,0.00001082345,0.0002106365,0.0001637082,7.174858e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007518497,"about_ca_system_score_gemma":0.0002212976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006112949,"about_ca_topic_score_gemma":0.00004370144,"domain_scores_codex":[0.998234,0.0001198478,0.0005273414,0.0002480716,0.0006708837,0.0001998804],"domain_scores_gemma":[0.9994707,0.000018539,0.000211115,0.0001166292,0.0001267327,0.00005628235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001599935,0.00006748181,0.0004065688,0.000003519013,0.00001800231,0.000305993,0.00009836142,0.2713985,0.726736,0.00002443582,0.00001836107,0.0007628275],"study_design_scores_gemma":[0.001285192,0.0003416063,0.0003021941,0.0000494686,0.000006350866,0.0004439695,0.0004290397,0.006205544,0.9881114,0.00008248002,0.002564328,0.0001783835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993066,0.002019103,0.003625385,0.000472191,0.0004565231,0.0001254955,0.00001369788,0.000002841144,0.000218737],"genre_scores_gemma":[0.9963154,0.0001200649,0.003226286,0.0001425407,0.0001167388,0.000004565624,0.000005134227,0.00001348293,0.0000557905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2651929,"threshold_uncertainty_score":0.4908802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01503510101894046,"score_gpt":0.3238817751934694,"score_spread":0.308846674174529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}