{"id":"W4293030248","doi":"10.3390/ijms23179538","title":"Vitelline Membrane Protein 26 Mutagenesis, Using CRISPR/Cas9, Results in Egg Collapse in Plutella xylostella","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Fujian Agriculture and Forestry University; National Natural Science Foundation of China","keywords":"Vitelline membrane; Biology; Plutella; Mutant; Yolk; Gene; Frameshift mutation; Molecular biology; Genetics; Oocyte; Exon; Embryo; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008041723,0.000414529,0.0002055332,0.000196565,0.0001588699,0.000213732,0.0002183108,0.0003033827,0.001499389],"category_scores_gemma":[0.00009123254,0.0001572328,0.0003741281,0.0001352466,0.0002180653,0.0001266783,0.0003167904,0.0005933308,0.0005409502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002748716,"about_ca_system_score_gemma":0.0001680162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001602369,"about_ca_topic_score_gemma":0.001553846,"domain_scores_codex":[0.9999148,0.000008513656,0.000008446661,0.0000238775,0.00002744308,0.00001698274],"domain_scores_gemma":[0.9999043,0.00001523527,0.00003867516,0.000009136651,0.000006286269,0.00002643354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003829436,0.000005790047,0.0001385098,0.00002654397,0.000003195855,0.0001244906,0.00001463957,0.00007003764,0.9990659,0.00005346252,0.0000354342,0.0004237184],"study_design_scores_gemma":[0.00002896211,0.0001204283,0.01464429,0.00001527684,0.00002137025,0.0008107158,0.0000886314,0.002257823,0.97778,0.00007791007,0.004140508,0.00001412917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929704,0.0006269238,0.003552172,0.00009274604,0.00003676286,0.00001978605,0.001066176,0.0002355743,0.001399429],"genre_scores_gemma":[0.9924318,0.0002714095,0.001409166,0.00004032311,0.000003476817,0.00002456185,0.000996,0.00007484182,0.004748472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001602369,"threshold_uncertainty_score":0.005015969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01503510101894046,"score_gpt":0.3238817751934694,"score_spread":0.308846674174529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}