{"id":"W4293036901","doi":"10.1186/s13063-022-06601-5","title":"A double-blind clinical trial to compare the efficacy and safety of a multiple amino acid-based ORS with the standard WHO-ORS in the management of non-cholera acute watery diarrhea in infants and young children: “VS002A” trial protocol","year":2022,"lang":"en","type":"article","venue":"Trials","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Foreign, Commonwealth and Development Office; International Centre for Diarrhoeal Disease Research, Bangladesh; Global Affairs Canada","keywords":"Medicine; Diarrhea; Cholera; Internal medicine; Randomized controlled trial; Oral rehydration therapy; Bloody diarrhea; Clinical trial; Clinical endpoint; Pediatrics; Gastroenterology; Population; Virology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006513958,0.0038881,0.006879984,0.0009199791,0.001249099,0.001673519,0.002175676,0.004983572,0.02011921],"category_scores_gemma":[0.006152758,0.001309445,0.002589007,0.000854914,0.002696912,0.001938642,0.0009138589,0.00476122,0.003313095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001343345,"about_ca_system_score_gemma":0.004482161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008721178,"about_ca_topic_score_gemma":0.001725879,"domain_scores_codex":[0.9965085,0.002054557,0.0002704384,0.0004844638,0.000274354,0.0004075512],"domain_scores_gemma":[0.9961044,0.00106099,0.0009065658,0.0003671082,0.0005135186,0.001047375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9873174,0.007722668,0.0000971331,0.0008400211,0.000283497,0.00001445353,0.00001985839,0.000106762,0.0005813162,0.0001230309,0.0005143042,0.002379521],"study_design_scores_gemma":[0.9587268,0.04017309,0.0001943302,0.00004712845,0.0001064024,0.000005853542,0.000006389355,0.0001431193,0.0001008308,0.00009433914,0.0003942678,0.0000075239],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.4887785,0.006530624,0.004865489,0.002368178,0.004571009,0.4778485,0.006146912,0.0006973549,0.008193477],"genre_scores_gemma":[0.3666187,0.003017814,0.008432838,0.002948289,0.001595695,0.6045482,0.002700462,0.00005490182,0.01008302],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.02011921,"threshold_uncertainty_score":0.06730551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1411547342747714,"score_gpt":0.4583862615182261,"score_spread":0.3172315272434548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}