{"id":"W4293088119","doi":"10.1055/s-0042-1755272","title":"Unraveling the Complexity of Liver Disease One Cell at a Time","year":2022,"lang":"en","type":"review","venue":"Seminars in Liver Disease","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Chan Zuckerberg Initiative","keywords":"Disease; Liver disease; Bioinformatics; Chronic liver disease; Biology; Computational biology; Medicine; Pathology; Cirrhosis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002564739,0.0004247974,0.0007094599,0.00008793608,0.0001647714,0.00001822695,0.0007151075,0.0001572798,0.0007357419],"category_scores_gemma":[0.00007619063,0.000359653,0.0006882289,0.0001994206,0.0004593276,0.000003937346,0.0005727983,0.0003090052,0.0000416698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001202195,"about_ca_system_score_gemma":0.0004155549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008393238,"about_ca_topic_score_gemma":0.0000257566,"domain_scores_codex":[0.9977949,0.0003822824,0.0005071319,0.0006464196,0.0003217199,0.0003475895],"domain_scores_gemma":[0.9984406,0.00008397235,0.0002783393,0.000863943,0.00003694782,0.0002961822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004461206,0.009044385,0.002096594,0.1107845,0.001411098,0.00159876,0.001130869,0.0003448293,0.004189773,0.000398569,0.0171156,0.8474239],"study_design_scores_gemma":[0.0004083452,0.0001210041,0.0003423448,0.00279751,0.001427379,0.000004798945,0.00001115557,0.0002379437,0.0001044773,0.00006701912,0.9938327,0.0006453346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00280118,0.9946604,0.00001738075,0.00001703032,0.0001470614,0.0008028104,0.001164563,0.00001139843,0.0003781826],"genre_scores_gemma":[0.003345774,0.9923016,0.0001099831,0.0001033371,0.000178165,0.0001100108,0.001919165,0.00007506881,0.001856925],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9767171,"threshold_uncertainty_score":0.9998856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06554367912488615,"score_gpt":0.2673306242158797,"score_spread":0.2017869450909936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}