{"id":"W4293148612","doi":"10.1055/s-0042-1747712","title":"Tezepelumab efficacy in patients with severe, uncontrolled asthma and comorbid nasal polyps in NAVIGATOR","year":2022,"lang":"en","type":"article","venue":"Pneumologie","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada)","funders":"","keywords":"Thymic stromal lymphopoietin; Medicine; Asthma; Monoclonal antibody; Nasal polyps; Internal medicine; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009473594,0.000426136,0.00138703,0.0001835923,0.0003469055,0.0005799082,0.0003282086,0.0006113269,0.002231634],"category_scores_gemma":[0.0008687741,0.0002060844,0.001369905,0.0002907196,0.0003420628,0.0005159592,0.0002818854,0.001515127,0.000258372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004583129,"about_ca_system_score_gemma":0.000673418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006578728,"about_ca_topic_score_gemma":0.003225678,"domain_scores_codex":[0.9996684,0.00009023965,0.0000360262,0.0000747688,0.00005575246,0.00007482771],"domain_scores_gemma":[0.9993016,0.0002032305,0.0001830265,0.00003099738,0.00004846788,0.0002327146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3177028,0.006834095,0.2408942,0.005198306,0.007127429,0.002343317,0.0004877411,0.002942179,0.05789226,0.0008292246,0.01493905,0.3428094],"study_design_scores_gemma":[0.1955125,0.204756,0.5370102,0.0009478746,0.007511371,0.008630724,0.0004344941,0.003606056,0.008875663,0.001317292,0.03119204,0.0002058548],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97062,0.02144936,0.0003782071,0.000911609,0.0001657245,0.0004351904,0.00150366,0.00008011972,0.004456072],"genre_scores_gemma":[0.99134,0.004060043,0.0006002945,0.001088905,0.0002477245,0.000285573,0.001725085,0.00001127776,0.0006410941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002231634,"threshold_uncertainty_score":0.007465541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00785445735233414,"score_gpt":0.2378997805299516,"score_spread":0.2300453231776174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}