{"id":"W4293178288","doi":"10.1111/acel.13700","title":"A gut‐centric view of aging: Do intestinal epithelial cells contribute to age‐associated microbiota changes, inflammaging, and immunosenescence?","year":2022,"lang":"en","type":"review","venue":"Aging Cell","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Multiple Sclerosis Society of Canada","keywords":"Immunosenescence; Biology; Immune system; Gut flora; Immunology; Immunity; Homeostasis; Intestinal epithelium; Epithelium; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006281136,0.000599315,0.001374444,0.0002673629,0.0001914264,0.00007281578,0.0006015161,0.0002940697,0.00007177961],"category_scores_gemma":[0.00007992833,0.00059122,0.000306936,0.0004776343,0.0001014563,0.000003496099,0.0008505618,0.0005255105,0.00002109584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001384154,"about_ca_system_score_gemma":0.0004598857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002507384,"about_ca_topic_score_gemma":0.00007061896,"domain_scores_codex":[0.9971245,0.0003734889,0.0007341992,0.0008578901,0.0001696948,0.0007402425],"domain_scores_gemma":[0.9982958,0.00008343157,0.0007003712,0.0006094221,0.0001039462,0.0002070117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002183179,0.0002496008,0.00006573679,0.018148,0.0002998722,0.000135411,0.000433092,0.000001473902,0.5667726,0.000008282285,0.006020392,0.4078437],"study_design_scores_gemma":[0.000494404,0.0002100137,0.00003127813,0.003234897,0.0003698179,0.0000809059,0.00002771352,4.079028e-7,0.00504177,0.000002284299,0.9899368,0.0005696506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002994415,0.9948041,0.00002843316,0.00007290534,0.0004795326,0.001025247,0.0004391375,0.00002610506,0.0001300536],"genre_scores_gemma":[0.001683499,0.9952791,0.0002283066,0.0003028572,0.0002103863,0.00004467463,0.00110972,0.00009624733,0.001045211],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9839165,"threshold_uncertainty_score":0.9996539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822181382541926,"score_gpt":0.2806906890686426,"score_spread":0.2624688752432234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}