{"id":"W4293178288","doi":"10.1111/acel.13700","title":"A gut‐centric view of aging: Do intestinal epithelial cells contribute to age‐associated microbiota changes, inflammaging, and immunosenescence?","year":2022,"lang":"en","type":"review","venue":"Aging Cell","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Multiple Sclerosis Society of Canada","keywords":"Immunosenescence; Biology; Immune system; Gut flora; Immunology; Immunity; Homeostasis; Intestinal epithelium; Epithelium; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005304771,0.0008348301,0.001117209,0.001724655,0.0003337182,0.00106597,0.000834675,0.001463643,0.002805902],"category_scores_gemma":[0.0007037984,0.0001797225,0.0003459443,0.001762186,0.0006595596,0.002217015,0.0008527889,0.001933143,0.001568554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005180244,"about_ca_system_score_gemma":0.00108611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006076718,"about_ca_topic_score_gemma":0.001025177,"domain_scores_codex":[0.9998919,0.00002017098,0.00001586131,0.00001979341,0.00003784044,0.00001447863],"domain_scores_gemma":[0.9997391,0.0001114679,0.00002903793,0.000008174651,0.00007426135,0.00003787126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001133881,0.00006295458,0.0003553703,0.01743933,0.0001030731,0.0004537121,0.0001849742,0.0002845472,0.002835652,0.01135758,0.05480563,0.9120039],"study_design_scores_gemma":[0.00001151463,0.0001073309,0.001296181,0.00469632,0.000123371,0.001845159,0.0001757641,0.00008222325,0.0003823201,0.005133461,0.9861233,0.00002301821],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008473162,0.9983132,0.0001230161,0.0005051148,0.0003786241,0.000001651027,0.000009049588,0.000005482234,0.000579183],"genre_scores_gemma":[0.0004659475,0.9985018,0.0001043381,0.0002771646,0.000336683,0.000002695376,0.00001348058,8.897184e-7,0.000297001],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002805902,"threshold_uncertainty_score":0.009386659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822181382541926,"score_gpt":0.2806906890686426,"score_spread":0.2624688752432234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}