{"id":"W4293181560","doi":"10.1139/cjpp-2022-0111","title":"Crosstalk among apoptosis, inflammation, and autophagy in relation to melatonin protective effect against contrast-induced nephropathy in rats","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Biomedical Research and Pathophysiology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Inflammasome; Oxidative stress; Melatonin; Apoptosis; Inflammation; Nephropathy; Kidney; Endocrinology; Internal medicine; Pharmacology; Nephrotoxicity; Chemistry; Medicine; Contrast-induced nephropathy; Diabetes mellitus; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000191235,0.0004343714,0.0004832618,0.0007121107,0.0002650402,0.0002184517,0.0001967366,0.0003679033,0.001107006],"category_scores_gemma":[0.0001135879,0.0002432992,0.0004119451,0.0002333006,0.0003492624,0.0003857351,0.0002016682,0.0009099676,0.0001176227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003124585,"about_ca_system_score_gemma":0.000463969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009168333,"about_ca_topic_score_gemma":0.001843601,"domain_scores_codex":[0.9998909,0.00001510053,0.00001107355,0.00002106656,0.00002010879,0.00004166595],"domain_scores_gemma":[0.9998784,0.000005475712,0.00004298307,0.000009237088,0.00001423115,0.00004960819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008682638,0.001684046,0.003297955,0.0002469606,0.00004633128,0.0003064781,0.0001315576,0.0001399894,0.9771837,0.0002460644,0.0001847067,0.007849506],"study_design_scores_gemma":[0.0004888148,0.01725182,0.04723433,0.00005414468,0.0002530601,0.0005681562,0.0003062048,0.001656833,0.9283658,0.0004707724,0.003309936,0.00004011052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948384,0.003028942,0.0008662779,0.00019646,0.00004938502,0.00004479543,0.0001648211,0.00005252818,0.0007583799],"genre_scores_gemma":[0.9938315,0.002076678,0.00127162,0.0001355244,0.00003052195,0.0001007458,0.0001961674,0.000008873098,0.002348275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001107006,"threshold_uncertainty_score":0.003703296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004258542743815,"score_gpt":0.2862065555521321,"score_spread":0.276163970124694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}