{"id":"W4293200057","doi":"10.3389/fimmu.2022.879775","title":"Arabinogalactan enhances Mycobacterium marinum virulence by suppressing host innate immune responses","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Microbiology; Virulence; Mycobacterium marinum; Biology; Innate immune system; Immune system; Secretion; Zebrafish; Arabinogalactan; Mycobacterium; Cell wall; Biochemistry; Bacteria; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118178,0.000344796,0.0002867428,0.0001941104,0.0001303865,0.0003559988,0.0001891679,0.0002578085,0.0008855871],"category_scores_gemma":[0.00009373821,0.0001191149,0.0001870183,0.000128217,0.0002054676,0.0001859626,0.0002388674,0.0006317225,0.0002600981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168529,"about_ca_system_score_gemma":0.000156424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003469131,"about_ca_topic_score_gemma":0.0005739655,"domain_scores_codex":[0.9998555,0.00002532813,0.00001224867,0.0000262175,0.00003875331,0.00004193958],"domain_scores_gemma":[0.9999152,0.000008586426,0.00002373797,0.0000103098,0.00001128427,0.00003086899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000815817,0.00002863645,0.0001395056,0.00002608476,0.000002190706,0.00002279601,0.00001038921,0.00002055159,0.9988159,0.00002544442,0.00002164268,0.0008053961],"study_design_scores_gemma":[0.0000209098,0.0006030711,0.01066168,0.00001325136,0.00002591728,0.0001575353,0.00006654023,0.001135139,0.9839339,0.00007984957,0.003295561,0.000006630651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953988,0.001525761,0.001165864,0.0001154379,0.00002373424,0.00001958468,0.0002583148,0.000132104,0.001360459],"genre_scores_gemma":[0.9959483,0.0005810668,0.001334867,0.00007056486,0.00001094333,0.0000204658,0.0003102134,0.00002071056,0.001702996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008855871,"threshold_uncertainty_score":0.00296253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009231991098947621,"score_gpt":0.2561993763241486,"score_spread":0.246967385225201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}