{"id":"W4293212291","doi":"10.1002/dta.3361","title":"Addressing recent challenges in isotope ratio mass spectrometry: Development of a method applicable to 1‐androstene‐steroids, 6α‐hydroxy‐androstenedione, and androstatrienedione","year":2022,"lang":"en","type":"article","venue":"Drug Testing and Analysis","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bundesministerium des Innern, für Bau und Heimat; World Anti-Doping Agency","keywords":"Isotope-ratio mass spectrometry; Chemistry; Chromatography; Analyte; Metabolite; Epitestosterone; Anabolism; Mass spectrometry; High-performance liquid chromatography; Steroid; Hormone; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001352975,0.0001968668,0.0007909634,0.000695132,0.0003677301,0.00002002288,0.00006442356,0.00002803413,0.00001558583],"category_scores_gemma":[0.0003063012,0.0001649949,0.00006057001,0.00228846,0.00005538016,0.00004986493,0.0002536847,0.000194708,5.597976e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008050079,"about_ca_system_score_gemma":0.00007323239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006891294,"about_ca_topic_score_gemma":0.00006577211,"domain_scores_codex":[0.9980819,0.0001255983,0.0004826144,0.0006425118,0.0003834362,0.0002839312],"domain_scores_gemma":[0.999112,0.0002313604,0.0001546905,0.000215054,0.0001444579,0.0001425132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006292317,0.0007215125,0.4235141,0.0006872467,0.00297853,0.0001281954,0.02506486,0.00257486,0.1856588,0.00008806081,0.00008031983,0.3578742],"study_design_scores_gemma":[0.007648778,0.001915294,0.827659,0.0006566418,0.004935356,0.0003548475,0.06269787,0.01727044,0.0647985,0.0009960344,0.00918187,0.001885369],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755597,0.01739641,0.002683894,0.002871555,0.00003456148,0.0004293037,0.0000228178,0.00004008158,0.000961743],"genre_scores_gemma":[0.9094496,0.0009649348,0.08902946,0.00007047067,0.00005636361,0.0001009415,0.00002352413,0.00001647861,0.000288169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4041449,"threshold_uncertainty_score":0.6728299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08453375662994989,"score_gpt":0.3200503942459198,"score_spread":0.2355166376159699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}