{"id":"W4293213678","doi":"10.3389/fcell.2022.968166","title":"Characterization of the roles of amphiregulin and transforming growth factor β1 in microvasculature-like formation in human granulosa-lutein cells","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Amphiregulin; Corpus luteum; Cell biology; Angiogenesis; Photostimulation; Small interfering RNA; SMAD; Gene knockdown; Biology; Signal transduction; Transforming growth factor; Internal medicine; Chemistry; Endocrinology; Cancer research; Epidermal growth factor; Receptor; Cell culture; Ovary; Transfection; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098788,0.00009201635,0.0001129147,0.0001926424,0.0001414588,0.0001626191,0.00008184655,0.00015855,0.0004222792],"category_scores_gemma":[0.00009640695,0.00007256243,0.000167921,0.0001337648,0.00008697284,0.0001425011,0.00009634281,0.0002116818,0.0001237987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001340748,"about_ca_system_score_gemma":0.0001387316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003791302,"about_ca_topic_score_gemma":0.0004484526,"domain_scores_codex":[0.9999552,0.000005384897,0.000003748968,0.00001027384,0.00001268476,0.00001286458],"domain_scores_gemma":[0.9999624,0.0000078405,0.000008862008,0.0000040233,0.000006494439,0.00001046939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008105065,0.00001663239,0.0008909945,0.00004546022,0.000003557413,0.0001258313,0.00003684874,0.00003081253,0.9963537,0.0001678321,0.00002354609,0.002223702],"study_design_scores_gemma":[0.00005001,0.0003713009,0.07496643,0.00001770772,0.00004475264,0.001665189,0.0001525512,0.002069045,0.9095258,0.0002151069,0.01091317,0.000009018784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918235,0.003101117,0.003308893,0.00008066204,0.00001112119,0.00005022042,0.0002585275,0.00002751233,0.001338522],"genre_scores_gemma":[0.9936795,0.001446231,0.002644067,0.00006272199,0.000008294599,0.00009024941,0.00070715,0.000006006534,0.001355709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004222792,"threshold_uncertainty_score":0.00141263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007155376402017358,"score_gpt":0.2022098191752548,"score_spread":0.1950544427732374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}